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is a necrotrophic pathogen that causes grey mold in many plant species, including crops and model plants of angiosperms. also infects and colonizes the bryophyte (previously ), which perceives the pathogen and activates defense mechanisms. However, these defenses are not sufficient to stop fungal invasion, leading finally to plant decay. To gain more insights into infection and virulence strategies displayed during moss colonization, we performed genome wide transcriptional profiling of during different infection stages. We show that, in total, 1015 genes were differentially expressed in moss tissues. Expression patterns of upregulated genes and gene ontology enrichment analysis revealed that infection of tissues by depends on reactive oxygen species generation and detoxification, transporter activities, plant cell wall degradation and modification, toxin production and probable plant defense evasion by effector proteins. Moreover, a comparison with available RNAseq data during angiosperm infection, including , suggests that has virulence and infection functions used in all hosts, while others are more specific to or angiosperms.
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http://dx.doi.org/10.3390/jof7010011 | DOI Listing |
Trop Doct
September 2025
Associate Professor, Department of Paediatrics, All India Institute of Medical Sciences, Bibinagar, India.
Scrub typhus, caused by , is a zoonotic infection endemic to the Asia-Pacific region. Its severity ranges from mild illness to life-threatening complications and case fatality rate upto 30%, highlighting the importance of early diagnosis. This study analyzed the clinical profile and pregnancy outcomes of 34 pregnant women diagnosed with scrub typhus at a tertiary care and referral centre.
View Article and Find Full Text PDFWorld J Surg
September 2025
Department of Hepatobiliary-Pancreatic Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Background: Achieving R0 resection in hepatopancreatobiliary (HBP) surgery frequently necessitates venous resection and reconstruction. Autologous grafts offer a promising solution, particularly in complex resections where infection risk or graft availability limit the use of synthetic or donor grafts. However, clinical data on the outcomes of autologous venous grafts remain limited.
View Article and Find Full Text PDFVet Pathol
September 2025
Cornell University, Ithaca, NY.
Mycobacteria ( family) comprise five genera (, , , , and ), which include relevant animal and human pathogens. Histology is a rapid method for preemptively diagnosing mycobacteriosis, contributing to surveillance, control, and eradication. A constraint on histology is the limited sensitivity and specificity of acid-fast stains, as the number of detectable bacilli in formalin-fixed paraffin-embedded (FFPE) tissue varies and other microorganisms are acid-fast positive.
View Article and Find Full Text PDFInfluenza Other Respir Viruses
September 2025
World Health Organization Regional Office for Europe, Copenhagen, Denmark.
Background: Few studies have evaluated COVID-19 vaccine effectiveness (VE) in middle-income countries, particularly in eastern Europe. We aimed to estimate COVID-19 VE against SARS-CoV-2-confirmed hospitalizations and severe outcomes in Kosovo.
Methods: We conducted a test-negative case-control study using data from Kosovo's severe acute respiratory infection (SARI) sentinel surveillance system from January 2022 to June 2024.
Vet Pathol
September 2025
Tulane National Primate Research Center, Covington, LA.
is a -like bacteria associated with watery diarrhea in humans and is infrequently reported in nonhuman primate (NHP) populations. While clinical and microscopic features in humans are indistinguishable from spp. infection, descriptions of -associated colitis in NHP are lacking.
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