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http://dx.doi.org/10.1016/j.jacep.2020.08.040 | DOI Listing |
J Neurosurg Case Lessons
September 2025
Department of Neurosurgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Background: Anaplastic lymphoma kinase (ALK)-positive primary CNS anaplastic large cell lymphoma (ALCL) is an extremely rare pediatric malignancy. Its radiological appearance often mimics infectious or glial lesions, complicating diagnosis and delaying treatment.
Observations: The authors report the case of a 10-year-old immunocompetent female who presented with absence seizures and vomiting.
Dis Esophagus
October 2025
Department of Surgery, Keio University School of Medicine, Tokyo, Japan.
Clinical practice guidelines for esophagogastric junction cancer (EGJ GLs) were published in 2023. In order to evaluate how EGJ GLs have been adopted into clinical practice worldwide and to identify any outstanding clinical questions to be addressed in the next edition, this survey was conducted. An electronic questionnaire was developed.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
September 2025
Department of Neuroscience, The Scripps Research Institute, San Diego, CA 92037.
Microglia regulate neuronal circuit plasticity. Disrupting their homeostatic function has detrimental effects on neuronal circuit health. Neuroinflammation contributes to the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), with several microglial activation genes linked to increased risk for these conditions.
View Article and Find Full Text PDFPLoS Comput Biol
September 2025
Université Grenoble Alpes, CNRS, Grenoble INP, TIMC, Grenoble, France.
Background And Objectives: We present a new Finite Element (FE) tongue model that was designed to precisely account for 3D tongue shapes produced during isolated French speech sounds by a male individual (RS). Such a high degree of realism will enable scientists to precisely and quantitatively assess, in a speaker-specific manner, hypotheses about speech motor control and the impact of tongue anatomy, muscle arrangements, and tongue dynamics in this context.
Methods: The shape and topology of the FE model were generated from 3D high resolution orofacial MR images of RS having his tongue in "neutral" posture.
Circulation
September 2025
Cardiology Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Italy (M.P.M).
Cardiac adipose tissue is normally present in the epicardium, but a variable amount can also be present in the myocardium, particularly in the subepicardial regions of the right ventricular anterolateral and apical regions. Pathological adipose tissue changes may occur in both ischemic (previous myocardial infarction) and nonischemic (previous myocarditis, arrhythmogenic cardiomyopathy, lipomatous hypertrophy of the interatrial septum, cardiac lipomas and liposarcomas) conditions, with or without extensive replacement-type myocardial fibrosis. Cardiac magnetic resonance is the gold standard imaging technique to characterize myocardial tissue changes and to distinguish between physiological and pathological cardiac fat deposits.
View Article and Find Full Text PDF