Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Spontaneous portosystemic shunts (SPSS) are common in cirrhosis. Their characterization and clinical implications remain unclear.
Aims: To devise a system of assessment of these shunts, and assess their clinical implications METHODS: We retrospectively studied patients with cirrhosis who underwent imaging in a liver transplant program. A novel index was computed to assess total SPSS -the diameter of a circle having an area equivalent to the sum of the areas of all the existing shunts. This 'SPSS equivalent diameter' was compared with the clinical variables.
Results: Among 127 patients, 70% (CI 62-77) had SPSS, and 57% (CI 62-77) had multiple SPSS. The risk for SPSS was related to the severity of cirrhosis (Child-Pugh B/C vs. A: OR 2.4 CI 1.1-5.4) and alcoholic aetiology (OR 2.9 CI 1.2-7.1). The SPSS equivalent diameter was related to a history of HE, cognitive impairment (EEG/PHES) and ammonia(p<0.05). The diameter of the inferior cava vein >19.5 mm was a predictor of large SPSS (AUC 0.77, CI:0.68-0.87, p ≤ 0.001).
Conclusions: The SPSS equivalent diameter, a comprehensive assessment of portosystemic shunting, was associated with severity of liver disease, hyperammonemia, and cognitive dysfunction. The diameter of the inferior vena cava was a good predictor of SPSS.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.dld.2020.11.020 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Effect of the Nurse's Compassionate Speech on the Pain Associated With Intravenous Catheter Insertion in Premature Neonates.
J Perinat Neonatal Nurs
September 2025
Author Affiliations: Student Research Committee School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran (Ms Omidvar); Department of pediatric nursing, Nursing and Midwifery Care Research Center, Department of pediatric nursing, Mashhad University ofMedical Sciences, Ma
Background: Venipuncture is a common and painful procedure in the neonatal intensive care unit (NICU), Thus, there is a necessity for cost-effective, safe, and nonpharmacological interventions to alleviate pain associated with frequent and painful procedures in infants.
Objective: This study aimed to investigate the effect of compassionate speech by nurses on the pain caused by venipuncture in premature infants.
Method: This quasi-experimental study was conducted on 65 premature infants admitted to the neonatal intensive care units of the Imam Reza and Qaem hospitals in Mashhad, Iran.
Factors and Disease-Specific Outcomes Associated With Treatment Delays in Osteosarcoma: A Population-Based Retrospective Cohort Study.
J Surg Oncol
September 2025
School of Medicine, Creighton University; Omaha, Nebraska, USA.
Introduction: Time to initiation of therapy in oncological care is an influential factor in disease progression and survival outcomes in many cancer types. We aim to identify factors associated with delayed time to treatment (TTT) in high-grade osteosarcoma and its relationship to disease-specific survival (DSS).
Methods: The SEER database was queried for biopsy-confirmed cases of high-grade osteosarcoma between 2000 and 2021 using ICD-O-3 histology codes 9180/3-9194/3 and primary site codes C40.
Randomized Clinical Trial on the Efficacy of Oral Tranexamic Acid Versus Topical Tranexamic Acid in Treatment of Melasma.
J Cosmet Dermatol
September 2025
Department of Medicine, Yazd Branch, Islamic Azad University, Yazd, Iran.
Background: Melasma is a prevalent skin condition that primarily affects females of reproductive age. Despite the various available treatments, managing melasma is challenging due to frequent relapses and partial responses. Tranexamic acid (TXA) has gained attention as a potential treatment because of its antifibrinolytic and anti-melanogenic properties.
View Article and Find Full Text PDFKnowledge of post-cesarean home care among postpartum mothers in Central Tanzania: Baseline findings from a quasi-experimental study.
Womens Health (Lond)
September 2025
Department of Clinical Nursing, School of Nursing, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Background: The increasing rate of cesarean section births is a global concern, including in Tanzania, where cesarean section births account for 11% of live births. Following a cesarean section, mothers are commonly discharged early to reduce ward congestion; as a result, they are required to receive care at home. However, evidence indicates that mothers receive limited or no information on post-cesarean section home care, which increases the risk of complications.
View Article and Find Full Text PDFEXPRESS: Effects of Magnesium and Potassium on Insulin Resistance and Blood Sugar Level among Insomniac Patients with Diabetes Mellitus-A Randomized Control Trial.
J Investig Med
September 2025
Department of Physiology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Aims: To compare the effect of magnesium and potassium on insulin resistance and blood sugar levels among insomniac patients with diabetes mellitus.
Methods: A randomized controlled study was conducted on 320 subjects enrolled in placebo (T1), Magnesium (T2), Potassium (T3) and Magnesium + Potassium (T4) treatment groups. Pre- and post-trial blood sugar and insulin levels were analyzed through blood.