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http://dx.doi.org/10.1007/s00268-020-05871-x | DOI Listing |
Lancet Diabetes Endocrinol
July 2025
Division of Endocrinology, Diabetes and Metabolism, Weill Cornell Medicine New York Presbyterian, New York, NY, USA.
Controlling weight and cardiovascular risk factors is paramount in type 2 diabetes management; however, the definition and feasibility of remission warrant closer examination. Type 2 diabetes remission, typically attained through weight loss, appears to be a temporary state based on the 2021 consensus definition, with most individuals experiencing weight regain and relapse of the condition. Although sustained type 2 diabetes remission is possible for some individuals and is associated with improved quality of life and reduced risk for microvascular and macrovascular complications, no conclusive evidence exists to show that achieving normoglycaemia and substantial weight loss without glucose-lowering medications is more beneficial than with them.
View Article and Find Full Text PDFJ Am Coll Cardiol
June 2025
Respiratory and Immunology Biometrics and Statistical Innovation, Biopharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.
Analyses using repeat hospitalizations (HFHs) are common in heart failure trials and typically assume that such repeat events occur randomly over time. Also, many think that using repeat events enhances statistical power. This article challenges those assumptions, using data from 4 heart failure trials of sodium-glucose cotransporter 2 inhibitors.
View Article and Find Full Text PDFMed J Armed Forces India
February 2024
Professor & Head (Anatomy), Kasturba Medical College, Manipal, Udupi, Karnataka, India.
Background: Soft cadavers are becoming increasingly popular for surgical skills development in competency-based medical education curricula. However, few studies evaluate this strategy's viability, dependability, and validity, particularly in India. This study intends to investigate embalming procedures and procedural skills practices at medical institutions.
View Article and Find Full Text PDFOral Oncol
July 2025
Department of Otolaryngology Head and Neck Surgery, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Institute of Oncology, Davidoff Center, Rabin Medical Center, Petach Tikva, Israel. Electronic address:
Objective: Previous studies of Lymph Node Yield (LNY) for neck dissection in Oral Cavity Squamous Cell Carcinoma (OCSCC) have shown LNY of 18 or more lymph nodes to be of prognostic value. This study aims to evaluate the prognostic implications of LNY, number of metastatic nodes, and Lymph Node Ratio (LNR) in clinical N0 OCSCC.
Methods: We retrospectively analyzed 118 patients who underwent elective neck dissection for OCSCC at Rabin Medical Center (2000-2020).
Orthop J Sports Med
May 2025
Department of Orthopaedics and Traumatology, Gazi University Faculty of Medicine, Ankara, Turkey.
Background: An increased posterior tibial slope (PTS) has been shown to be a risk factor for anterior cruciate ligament (ACL) ruptures, but the difference in the mean PTS between patients with ACL ruptures and patients with intact ACLs is only approximately 1°, and the PTS has a wide range between 1° and 22°. Therefore, an ACL rupture may be associated with other morphological differences along with the PTS.
Purpose: To evaluate whether the predictive value of the PTS can be increased with new parameters associated with the proximal tibia, distal femur, and extensor mechanism.