Resonance assignments of La protein RRM domain from Trypanosoma brucei.

Biomol NMR Assign

Department of Pulmonary and Critical Care Medicine, Affiliated Hospital of Jining Medical University, Jining, 272029, Shandong, China.

Published: April 2021


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Article Abstract

The autoantigen La protein is a conserved component of eukaryotic ribonucleoprotein complexes that binds the 3' poly(U) sequences of nascent RNA polymerase III transcripts to assist folding and maturation. This specific recognition is mediated by the N-terminal domain (NTD) of La, which comprises a La motif and an RNA recognition motif (RRM). Here, we report near complete H, C and N backbone and sidechain assignments for the RRM domain of La protein from Trypanosoma brucei.

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http://dx.doi.org/10.1007/s12104-020-09980-5DOI Listing

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