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Deep learning has emerged as a leading machine learning tool in object detection and has attracted attention with its achievements in progressing medical image analysis. Convolutional Neural Networks (CNNs) are the most preferred method of deep learning algorithms for this purpose and they have an essential role in the detection and potential early diagnosis of colon cancer. In this article, we hope to bring a perspective to progress in this area by reviewing deep learning practices for colon cancer analysis. This study first presents an overview of popular deep learning architectures used in colon cancer analysis. After that, all studies related to colon cancer analysis are collected under the field of colon cancer and deep learning, then they are divided into five categories that are detection, classification, segmentation, survival prediction, and inflammatory bowel diseases. Then, the studies collected under each category are summarized in detail and listed. We conclude our work with a summary of recent deep learning practices for colon cancer analysis, a critical discussion of the challenges faced, and suggestions for future research. This study differs from other studies by including 135 recent academic papers, separating colon cancer into five different classes, and providing a comprehensive structure. We hope that this study is beneficial to researchers interested in using deep learning techniques for the diagnosis of colon cancer.
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http://dx.doi.org/10.1016/j.compbiomed.2020.104003 | DOI Listing |
Dig Dis Sci
September 2025
Department of Gastrointestinal Surgery, Meizhou People's Hospital, Meizhou Academy of Medical Sciences, No. 63, Xinfeng Road, Meijiang District, Meizhou, 514031, Guangdong, China.
J Egypt Natl Canc Inst
September 2025
National Cancer Institute of Cairo University, Giza, Egypt.
Objectives: To balance the extended functional urinary voiding and morbidity outcomes amid Ileal W and Y-shaped contrasted to spherical ileocoecal (IC) orthotopic bladders subsequent prostate-sparing radical cystectomy (PRC) versus standard radical cystoprostatectomy (RC).
Material And Methods: Two hundred eight male bladder cancer patients were grouped into 98 RC followed by 43-W, 31-Y, and 23-IC in comparison to 110 PRC followed by 35-W, 37-Y, and 38-IC. The functional voiding outcomes were determined by detailed patients' interview and urodynamic studies (UDS).
Int J Biol Macromol
September 2025
Nanotechnology Laboratory, TRANSCEND Research Center, Regional Institute of Oncology, 2-4 General Henri Mathias Berthelot Street, 700483, Iași, Romania; Faculty of Chemistry, Al. I. Cuza University, 11- Carol I Bvd., 700506, Iasi, Romania. Electronic address:
This contribution discusses the design of bionanocomposites based on chitosan and MgAl layered double hydroxides (LDH) for cancer therapy. Compared to other studies, our approach was to pre-adsorb the metal chloride precursors of LDH on chitosan while the solution of metal precursors with and without H provided the acidic environment for polymer dissolution. The structure, morphology and chemical composition of the bionanocomposites were characterized by XRD, FTIR, TG, etc.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
Department of Tumor Biological Treatment, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, 213003, China; Jiangsu Engineering Research Center for Tumor Immunotherapy, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, 213003, China; Institute of Cell The
Despite its potential as a cancer immunotherapy, wild-type IL-2 is limited by dose-limiting toxicities, including vascular leak syndrome, and its strong activation of regulatory T cells (Tregs), which dampens anti-tumor immunity. These drawbacks are largely driven by IL-2's binding to IL-2Rα, and avoiding this interaction can reduce IL-2-associated toxicities, although it cannot completely eliminate them. To overcome these limitations, βγ-biased IL-2 variants (Non-α-IL-2) have been developed to selectively activate effector T and NK cells.
View Article and Find Full Text PDFLancet Gastroenterol Hepatol
October 2025
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy; Endoscopy Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy.
Background: Guidelines recommend leaving in situ rectosigmoid polyps diagnosed during colonoscopy that are 5 mm or smaller if the endoscopist optically predicts them to be non-neoplastic. However, no randomised controlled trial has been done to examine the efficacy and safety of this strategy.
Methods: This open-label, multicentre, non-inferiority, randomised controlled trial enrolled adults age 18 years or older undergoing colonoscopy for screening, surveillance, or clinical indications across four Italian centres.