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Lumps in the hand are a common presenting complaint in General Practice. We present the case of a 24-year-old male who presented to his General Practitioner with a painful lump in the dorsum of his right hand. He was referred to the sarcoma services where MRI and ultrasound examinations revealed an accessory Extensor Digitorum Brevis Manus muscle as the cause of the patient's symptoms. When patients present with a painful or discomforting lump in the dorsum of the hand during or after repetitive use, typically on flexion, a diagnosis of Extensor Digitorum Brevis Manus should be considered.
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http://dx.doi.org/10.1016/j.radcr.2020.09.003 | DOI Listing |
JBJS Essent Surg Tech
September 2025
Division of Hand and Reconstructive Microsurgery, Department of Orthopedics, Olympia Hospital & Research Centre, Trichy, Tamilnadu, India.
Background: Extensor indicis proprius (EIP) transfer augmented with proximal extensor pollicis longus (EPL) stump lengthening restores thumb extension and optimizes function in cases of chronic EPL tendon ruptures, which impair hand dexterity and fine motor skills. Traditional EIP-to-EPL transfers often disrupt the natural oblique course of the EPL around the Lister tubercle, leading to functional deficits. This dual-tendon transfer preserves anatomical alignment and improves thumb biomechanics, enhancing extension strength and the adduction moment arm at the carpometacarpal (CMC) joint.
View Article and Find Full Text PDFJBJS Essent Surg Tech
September 2025
Division of Hand and Reconstructive Microsurgery, Department of Orthopedics, Olympia Hospital & Research Centre, Trichy, Tamilnadu, India.
Background: Hemi-hamate osteochondral grafting is a surgical technique that is utilized to reconstruct the proximal interphalangeal (PIP) joint in cases of unstable dorsal fracture-dislocation with >50% articular surface involvement. However, hemi-hamate osteochondral grafting can be technically challenging, has been reported to have various technical modifications, and can lead to complications such as overstuffing of the joint. This surgical technique article describes successful PIP joint reconstruction with use of a hemi-capitate osteochondral graft, which may offer a viable alternative to hemi-hamate osteochondral graft.
View Article and Find Full Text PDFJ Mol Neurosci
September 2025
Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA.
Collagen type XX alpha 1 (COL20A1) was recently found to be highly concentrated in perisynaptic Schwann cells (PSCs), the synaptic glia of the neuromuscular junction (NMJ), suggesting that COL20A1 plays important roles in PSCs and at the NMJ. To investigate this possibility, we generated mice lacking Col20a1 only in Schwann cells (Col20a1-SCKO) and globally (Col20a1-gKO). PSCs and NMJs were morphologically unchanged in adult Col20a1-SCKO mice despite these conditional mice exhibiting gait abnormalities.
View Article and Find Full Text PDFClin Neurophysiol
August 2025
University of Chicago Medical Center, United States.
Objective: To evaluate the diagnostic potential of intermuscular coherence (IMC) measured from leg muscle pairs as an early-stage biomarker for amyotrophic lateral sclerosis (ALS).
Methods: Surface electromyography (sEMG) was recorded in neurotypical subjects and patients with early-stage ALS from muscle pairs: gastrocnemius lateralis-gastrocnemius medialis (GLGM), tibialis anterior-extensor digitorum brevis (TAED), and vastus lateralis-vastus medialis (VLVM). IMC within the 20-40 Hz range (IMCβγ) and the imaginary component of coherency in the 20-40 Hz range (ICOHβγ) were calculated.
Front Physiol
August 2025
Keizo Asami Institute, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
Introduction: The Environmental Enrichment (EE) promotes systemic responses through social, cognitive, sensory, and physical stimuli. However, its effects on hepatic and muscle oxidative balance, as well as on serum inflammation markers, remain unclear. Therefore, this study aimed to evaluate whether three weeks of EE could modulate hepatic and muscular oxidative balance and the inflammatory response in female C57BL/6 mice.
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