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In recent years, research and development of autonomous driving technology have gained much interest. Many autonomous driving frameworks have been developed in the past. However, building a safely operating fully functional autonomous driving framework is still a challenge. Several accidents have been occurred with autonomous vehicles, including Tesla and Volvo XC90, resulting in serious personal injuries and death. One of the major reasons is the increase in urbanization and mobility demands. The autonomous vehicle is expected to increase road safety while reducing road accidents that occur due to human errors. The accurate sensing of the environment and safe driving under various scenarios must be ensured to achieve the highest level of autonomy. This research presents Clothoid a unified framework for fully autonomous vehicles, that integrates the modules of HD mapping, localization, environmental perception, path planning, and control while considering the safety, comfort, and scalability in the real traffic environment. The proposed framework enables obstacle avoidance, pedestrian safety, object detection, road blockage avoidance, path planning for single-lane and multi-lane routes, and safe driving of vehicles throughout the journey. The performance of each module has been validated in K-City under multiple scenarios where Clothoid has been driven safely from the starting point to the goal point. The vehicle was one of the top five to successfully finish the autonomous vehicle challenge (AVC) in the Hyundai AVC.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570716 | PMC |
http://dx.doi.org/10.3390/s20185053 | DOI Listing |
Neural Netw
September 2025
School of Electronic Science and Engineering, Nanjing University, China. Electronic address:
The Segment Anything Model (SAM) is a cornerstone of image segmentation, demonstrating exceptional performance across various applications, particularly in autonomous driving and medical imaging, where precise segmentation is crucial. However, SAM is vulnerable to adversarial attacks that can significantly impair its functionality through minor input perturbations. Traditional techniques, such as FGSM and PGD, are often ineffective in segmentation tasks due to their reliance on global perturbations that overlook spatial nuances.
View Article and Find Full Text PDFAdv Sci (Weinh)
September 2025
Department of Occupational Health (Key Laboratory of Electromagnetic Radiation Protection, Ministry of Education), Army Medical University (Third Military Medical University), Chongqing, 400038, China.
Cadmium (Cd) is a heavy metal that exhibits strong carcinogenic properties and promotes breast cancer (BC) progression. Autophagic flux dysfunction is involved in Cd-induced BC progression, but the underlying molecular mechanisms remain unclear. Here, it is observed that impaired autophagic flux and metabolic reprogramming are notable features related to Cd-induced proliferation, migration, and invasion in BC cell lines, including T-47D and MCF-7 cells.
View Article and Find Full Text PDFSmall Sci
September 2025
Infrared photodetectors are crucial for autonomous driving, providing reliable object detection under challenging lighting conditions. However, conventional silicon-based devices are limited in their responsivity beyond 1100 nm. Here, a scallop-structured silicon photodetector integrated with tin-substituted perovskite quantum dots (PQDs) that effectively extends infrared detection is demonstrated.
View Article and Find Full Text PDFFront Biosci (Landmark Ed)
August 2025
Department of Hepatobiliary Surgery, General Hospital of Ningxia Medical University, 750004 Yinchuan, Ningxia Hui Autonomous Region, China.
Background: Mediator complex subunit 10 (MED10) serves as a critical regulator of eukaryotic gene expression by facilitating RNA polymerase II activity. Our investigation aims to characterize MED10's functional contributions and underlying molecular pathways in hepatocellular carcinoma (HCC) development.
Methods: MED10 expression patterns in HCC and their correlation with clinicopathological parameters and patient outcomes were examined using bioinformatics databases and immunohistochemistry.
CRISPR homing gene drive is a disruptive biotechnology developed over the past decade with potential applications in public health, agriculture, and conservation biology. This technology relies on an autonomous selfish genetic element able to spread in natural populations through the release of gene drive individuals. However, it has not yet been deployed in the wild.
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