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Article Abstract
The straightforward synthesis of -disubstituted formamides using a combination of 1,1,1,3,3,3-hexafluoroispropanol (HFIP) and HO is described. The unique features of HFIP allowed the utilization of a green oxidant such as HO, and the products, arising from an oxidation-rearrangement sequence, were obtained in good to high yields under smooth reaction conditions.
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