98%
921
2 minutes
20
Objectives: We report our experience with an emergency room (ER) shutdown related to an accidental exposure to a patient with coronavirus disease 2019 (COVID-19) who had not been isolated.
Setting: A 635-bed, tertiary-care hospital in Daegu, South Korea.
Methods: To prevent nosocomial transmission of the disease, we subsequently isolated patients with suspected symptoms, relevant radiographic findings, or epidemiology. Severe acute respiratory coronavirus 2 (SARS-CoV-2) reverse-transcriptase polymerase chain reaction assays (RT-PCR) were performed for most patients requiring hospitalization. A universal mask policy and comprehensive use of personal protective equipment (PPE) were implemented. We analyzed effects of these interventions.
Results: From the pre-shutdown period (February 10-25, 2020) to the post-shutdown period (February 28 to March 16, 2020), the mean hourly turnaround time decreased from 23:31 ±6:43 hours to 9:27 ±3:41 hours (P < .001). As a result, the proportion of the patients tested increased from 5.8% (N=1,037) to 64.6% (N=690) (P < .001) and the average number of tests per day increased from 3.8±4.3 to 24.7±5.0 (P < .001). All 23 patients with COVID-19 in the post-shutdown period were isolated in the ER without any problematic accidental exposure or nosocomial transmission. After the shutdown, several metrics increased. The median duration of stay in the ER among hospitalized patients increased from 4:30 hours (interquartile range [IQR], 2:17-9:48) to 14:33 hours (IQR, 6:55-24:50) (P < .001). Rates of intensive care unit admissions increased from 1.4% to 2.9% (P = .023), and mortality increased from 0.9% to 3.0% (P = .001).
Conclusions: Problematic accidental exposure and nosocomial transmission of COVID-19 can be successfully prevented through active isolation and surveillance policies and comprehensive PPE use despite longer ER stays and the presence of more severely ill patients during a severe COVID-19 outbreak.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431852 | PMC |
http://dx.doi.org/10.1017/ice.2020.376 | DOI Listing |
Int J Med Inform
September 2025
Department of Signal Theory and Communications and Telematics Engineering University of Valladolid, Paseo de Belén, 15, 47011 Valladolid, Spain. Electronic address:
Introduction: Insider threats pose a critical risk in healthcare environments, where Hospital Information Systems (HIS) manage sensitive patients data. Authorized users may intentionally or accidentally compromise data confidentiality, integrity, and availability. This study assessed information security practices from the perspective of healthcare professionals in Spanish medical centers.
View Article and Find Full Text PDFJ Anal Toxicol
September 2025
Department of Legal Medicine, College of Basic Medical Sciences, Inner Mongolia Medical University, Hohhot, China.
Free phenol and cresol isomers in human samples have drawn interest, particularly in the field of forensic toxicology. In this study, a simultaneous analytical method for the detection of unchanged phenol and three structural isomers of cresol in human blood was developed using GC-MS/MS. This method was applied to authentic human heart and peripheral vein blood samples obtained from a fatal intoxication case involving accidental exposure to liquified phenol containing cresol isomers.
View Article and Find Full Text PDFPediatr Allergy Immunol
September 2025
Department of Pediatrics and Child Health, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Food plays a unique role in culture and identity. For families managing food allergy, the role of food is complex and juxtaposed against the need to avoid known allergens, lest they risk an accidental exposure. While avoidance is simple in its instruction, the hidden prices of food allergy, namely the social and financial burdens on families, are substantial and fluid across the lifespan and in an era of rapid change in food allergy management and therapy.
View Article and Find Full Text PDFJ Biol Chem
September 2025
Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, 238 Baidi Road, Tianjin 300192, China. Electronic address:
Accidental internal or external exposure to gamma radiation can cause severe injury to the human body. The identification of an effective medication target has become particularly important for the treatment of radiation-induced injury. In this work, Caenorhabditis elegans was found to tolerate high-dose radiation when exposed to an extremely low-temperature environment (at 4°C) for 4 hours before irradiation.
View Article and Find Full Text PDFEcotoxicol Environ Saf
September 2025
Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, Anhui Province, China; Key Laboratory of Population Health Across Life Cycle (Anhui Medical University), Ministry of Education of the People's Republic of China, Hefei, Anhui Province, Chin
Background: Short-term exposure to ozone has been linked to increased mortality, but its role in temperature-health associations is still not fully understood. Beyond direct effects, ozone may influence mortality as both a factor modified by temperature and a mediator of temperature's impact.
Methods: We conducted a time-series study using quasi-Poisson generalized additive models (GAMs) to examine associations between short-term ozone exposure and cause-specific mortality in Hefei, China (2014-2022).