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Background: De Winter syndrome accounts for approximately 2% of all patients with acute anterior myocardial infarction admitted to the emergency department, and is characterized by severe stenosis of the left anterior descending coronary artery (LAD). The ECG changes are not recognized by ECG software, and poor understanding of the syndrome among physicians may lead to misdiagnosis, delayed reperfusion, and mortality.
Case Presentation: A 51-year-old male patient presented with a newly developed ECG pattern suggestive of de Winter Syndrome. Coronary angiography revealed anterior myocardial infarction. Based on the ECG and clinical manifestations, the patient was diagnosed with de Winter syndrome and underwent timely percutaneous coronary intervention to revascularize the left anterior descending artery (LAD). The patient showed good outcomes and no complications at 4 months after the operation.
Conclusions: This case highlights the importance of being aware of the possibility of de Winter syndrome in patients with symptoms of myocardial infarction but atypical ECG in order to conduct early revascularization and treatments.
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http://dx.doi.org/10.1186/s12872-020-01619-6 | DOI Listing |
Hum Genome Var
September 2025
Department of Pediatrics, Tokushima University Hospital, Kuramotocho, Tokushima, Japan.
Here we report a heterozygous missense variant in the ACTB gene, NM_001101.5:c.209C>T (p.
View Article and Find Full Text PDFItal J Pediatr
September 2025
Pediatric Unit, Meyer Children's Hospital IRCCS, Florence, Italy.
Background: Staphylococcal-scalded skin syndrome (SSSS) is a potentially life-threatening disorder characterized by superficial skin blistering caused by exfoliative toxins produced by Staphylococcus aureus. This study aimed to investigate SSSS in a cohort of children admitted at a tertiary pediatric hospital in Italy.
Methods: Patients discharged with the diagnosis of staphylococcal infection and of SSSS between January 2010 and March 2023 were retrospectively identified using ICD-9-CM codes (695.
BMC Cardiovasc Disord
September 2025
Department of Cardiology, the First People's Hospital of Yibin, Yibin, Sichuan, China.
Background: The de Winter electrocardiographic (ECG) pattern, characterized by upsloping ST-segment depression and tall T waves in leads V1-V6, is typically associated with proximal left anterior descending (LAD) artery occlusion. When combined with pronounced ST-segment elevation in lead aVR, it may indicate a more severe coronary artery involvement.
Case Presentation: A 36-year-old male smoker presented with acute chest pain for 2 h.
Microorganisms
July 2025
Epidemiology Unit, Regional Health Agency of Tuscany, 50141 Florence, Italy.
During the COVID-19 pandemic, some studies suggested that transmission events could originate from schools. This study aimed to evaluate early-warning methods for identifying asymptomatic COVID-19 cases by implementing screening programs in schools. This study was conducted between September 2021 and May 2023, employing a rotation-screening plan for COVID-19 detection on a sample of students aged 14 to 19 years attending secondary schools in the regions of Tuscany, Veneto, Apulia and Friuli-Venezia Giulia.
View Article and Find Full Text PDFBiomolecules
July 2025
Faculty of Health Sciences, Medical University of Warsaw, Żwirki i Wigury 61, 02-091 Warsaw, Poland.
The etiology of schizophrenia remains poorly understood. Although certain risk factors have been identified, effective preventive measures are still lacking. This study investigates potential preventive methods while focusing on the role of vitamin D and its status.
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