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Objective: Relative fundamental frequency (RFF) has been suggested as a potential acoustic measure of vocal effort. However, current clinical standards for RFF measures require time-consuming manual markings. Previous semi-automated algorithms have been developed to calculate RFF from microphone signals. The current study aimed to develop fully automated algorithms to calculate RFF from neck-surface accelerometer signals for ecological momentary assessment and ambulatory monitoring of voice.
Methods: Training a set of 2646 /vowel-fricative-vowel/ utterances from 317 unique speakers, with and without voice disorders, was used to develop automated algorithms to calculate RFF values from neck-surface accelerometer signals. The algorithms first rejected utterances with poor vowel-to-noise ratios, then identified fricative locations, then used signal features to determine voicing boundary cycles, and finally calculated corresponding RFF values. These automated RFF values were compared to the clinical gold-standard of manual RFF calculated from simultaneously collected microphone signals in a novel test set of 639 utterances from 77 unique speakers.
Results: Automated accelerometer-based RFF values resulted in an average mean bias error (MBE) across all cycles of 0.027 ST, with an MBE of 0.152 ST and -0.252 ST in the offset and onset cycles closest to the fricative, respectively.
Conclusion: All MBE values were smaller than the expected changes in RFF values following successful voice therapy, suggesting that the current algorithms could be used for ecological momentary assessment and ambulatory monitoring via neck-surface accelerometer signals.
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http://dx.doi.org/10.1016/j.jvoice.2020.06.001 | DOI Listing |
J Speech Lang Hear Res
September 2025
Department of Speech, Language, & Hearing Sciences, Boston University, MA.
Purpose: Hyperfunctional voice disorders are highly prevalent yet difficult to characterize objectively. Relative fundamental frequency (RFF) has the potential to characterize these disorders but faces limited clinical use due to intersubject variability in mean RFF values. This study examined whether RFF variability offers insights beyond traditional mean measures.
View Article and Find Full Text PDFElectromagn Biol Med
August 2025
Department of Physiology, Faculty of Medicine, Bandırma Onyedi Eylül University, Balıkesir, Turkey.
The aim of this study is to investigate the potential synergistic effects of agomelatine(AGM) and 2600 MHz radiofrequency(RF) field exposure on inflammation induced by chronic lipopolysaccharide(LPS) administration in rats. A total of 49 female Wistar albino rats were randomly divided into 7 groups( = 7 per group): Control, Sham, LPS, LPS+AGM,LPS+RF,AGM+RF, and LPS+AGM+RF. Animals in the RF groups were exposed to a 2600 MHz field (1 h/day for 15 days).
View Article and Find Full Text PDFJ Voice
July 2025
Department of Speech, Language, and Hearing Sciences, Boston University, Boston, MA. Electronic address:
Purpose: The purpose of this study was to establish normative thresholds for relative fundamental frequency (RFF) referencing individuals with typical voices.
Method: A total of 150 speakers (75 males, 75 females) without voice disorders were evenly divided into three age groups: 18-39, 40-64, and 65+ years. Each participant produced three repetitions of the utterances /ɑfɑ/, /ifi/, and /ufu/ at their typical pitch and loudness, which were recorded for analysis.
J Voice
July 2025
Department of Speech, Language, and Hearing Sciences, Boston University, Boston, MA 02215; Delsys, Inc., Natick, MA 01760; Altec, Inc., Natick, MA 01760.
Objectives: The purpose of this study was to validate PyRFF, a semi-automated software for calculating relative fundamental frequency (RFF). PyRFF was developed in Python, a widely used open source programming language, making it freely accessible and broadly applicable for researchers and clinicians. By providing an accessible tool for RFF extraction, PyRFF has the potential to facilitate wider adoption of RFF measures in both research and clinical settings.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
June 2025
Zhejiang Provincial Institute of Cultural Relics and Archaeology, Hangzhou, Zhejiang 310012, China.
The domestication of pigs () has had profound socioeconomic and ecological consequences. Although pigs are believed to have been independently domesticated in South China, the timing and initial mechanisms of this process remain debated. This study presents a microfossil analysis of pig dental calculus from two early Neolithic sites in the Lower Yangtze River region: Jingtoushan (8,300 to 7,800 cal.
View Article and Find Full Text PDF