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http://dx.doi.org/10.1104/pp.20.00646 | DOI Listing |
J Trauma Inj
June 2025
Department of Orthopaedics, All India Institute of Medical Sciences, Jodhpur (AIIMS Jodhpur), Jodhpur, India.
Purpose: Managing complex distal femur fractures presents technical challenges. Although the lateral locked plate has become standard for these fractures, failures are not uncommon when this device is used alone. Patients with nonunion of distal femur fractures following treatment with a single lateral locked plate were examined.
View Article and Find Full Text PDFPlant Sci
September 2025
Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou 730000, China; College of Life Sciences, Shaoxing University, Shaoxing, Zhejiang 312000, China. Electronic address:
In Arabidopsis, the root apical meristem consists of quiescent center (QC) and its surrounding stem cells, which form a stem cell niche (SCN) that develops into the root structure. The formation and maintenance of stem cells are regulated by hormones and transcription factors. Previous studies have shown that clathrin-mediated endocytosis impairs root growth; however, the underlying mechanisms remain unclear.
View Article and Find Full Text PDFCell Rep
May 2024
Institute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria. Electronic address:
Clathrin-mediated endocytosis (CME) is an essential process of cargo uptake operating in all eukaryotes. In animals and yeast, BAR-SH3 domain proteins, endophilins and amphiphysins, function at the conclusion of CME to recruit factors for vesicle scission and uncoating. Arabidopsis thaliana contains the BAR-SH3 domain proteins SH3P1-SH3P3, but their role is poorly understood.
View Article and Find Full Text PDFJ Plant Physiol
April 2024
Key Laboratory of Gene Editing for Breeding, Gansu Province, Key Laboratory of Cell Activities and Stress Adaptations, Ministry of Education, School of Life Sciences, Lanzhou University, Lanzhou, 730000, China. Electronic address:
Clathrin-mediated endocytosis (CME) is a highly conserved pathway that plays a crucial role in the endocytosis of plasma membrane proteins in eukaryotic cells. The pathway is initiated when the adaptor protein complex 2 (AP2) and TPLATE complex (TPC) work together to recognize cargo proteins and recruit clathrin. This review provides a concise overview of the functions of each subunit of AP2 and TPC, and highlights the involvement of CME in various biological processes, such as pollen development, root development, nutrient transport, extracellular signal transduction, auxin polar transport, hyperosmotic stress, salinity stress, high ammonium stress, and disease resistance.
View Article and Find Full Text PDFNat Cell Biol
March 2024
Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.
Clathrin-mediated endocytosis is an essential cellular internalization pathway involving the dynamic assembly of clathrin and accessory proteins to form membrane-bound vesicles. The evolutionarily ancient TSET-TPLATE complex (TPC) plays an essential, but ill-defined role in endocytosis in plants. Here we show that two highly disordered TPC subunits, AtEH1 and AtEH2, function as scaffolds to drive biomolecular condensation of the complex.
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