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http://dx.doi.org/10.1097/IJG.0000000000001586 | DOI Listing |
Retin Cases Brief Rep
September 2025
Retinal Disorders and Ophthalmic Genetics Division, Stein Eye Institute, University of California of Los Angeles, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.
Purpose: To describe a case of recalcitrant bilateral peripapillary pachychoroid syndrome (PPS) treated with high-dose (HD) intravitreal aflibercept injections.
Methods: Medical and imaging records were retrospectively evaluated. Multimodal imaging included ultra-widefield indocyanine green and fluorescein angiography and fundus autofluorescence.
Eye (Lond)
September 2025
Eye Center, Renmin Hospital of Wuhan University, Wuhan, China.
Background: The global prevalence of high myopia is rising, posing a significant public health concern. Limited research exists on risk factors for prelaminar schisis (PLS) and its impact on visual field changes in highly myopic eyes. Herein, we investigated clinical features of prelaminar schisis (PLS) in highly myopic eyes.
View Article and Find Full Text PDFNeurol Neuroimmunol Neuroinflamm
November 2025
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD.
Background And Objectives: Optical coherence tomography (OCT) allows evaluation of inter-eye differences (IEDs) in macular ganglion cell-inner plexiform layer (GCIPL) and peripapillary retinal nerve fiber layer (pRNFL) thicknesses to identify unilateral optic nerve involvement (UONI). UONI supports dissemination in space (DIS) as part of the 2024 revised McDonald diagnostic criteria for multiple sclerosis (MS). The OSCAR-IB quality control (QC) criteria identify suboptimal-quality OCT scans, which could potentially result in false-positive or false-negative UONI identification.
View Article and Find Full Text PDFInt J Ophthalmol
September 2025
Department of Optics, Pharmacology and Anatomy, University of Alicante, 03690 San Vicente del Raspeig, Alicante, Spain.
Aim: To assess whether the implantation of a posterior chamber phakic intraocular lens produces changes in optical coherence tomography (OCT) measurements of macular thickness (MT) and two parameters that define the structure of the optic nerve, the peripapillary nerve fiber layer (RNFL) and the Bruch's membrane opening-minimum rim width (BMO-MRW).
Methods: This nonrandomized prospective pre-post study included 86 eyes of 48 patients (age, 20-47y; axial length: 23.10-28.
J Clin Med
August 2025
General University Hospital Morales Meseguer, 30008 Murcia, Spain.
Attention deficit hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental disorder. As the retina is an extension of the central nervous system, retinal imaging may provide insights into the ADHD pathophysiology. The objective of this work was to evaluate structural retinal alterations using optical coherence tomography (OCT) in ADHD patients compared to neurotypical controls.
View Article and Find Full Text PDF