Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Unique pathways to adolescents' co-occurring internalizing/externalizing problems, a severe and common form of psychopathology, remain poorly delineated; this paucity of knowledge impedes the development of personalized interventions. We examined established measures of genetic risk and early childhood temperamental dimensions to clarify potentially distinct pathways to adolescents' co-occurring internalizing/externalizing problems. Participants were drawn from a longitudinal randomized controlled trial of a family-based intervention. The study employed multiple informants and methods, including observer ratings of toddlers' negative affectivity and behavioral inhibition, and primary caregiver ratings of toddlers' inhibitory control; internalizing and aggression polygenic risk scores (PRS) based on prior meta-genome-wide association studies (GWAS); and parents' and teachers' reports of adolescents' internalizing and externalizing problems. Higher levels of the aggression PRS indirectly predicted primary caregiver- and teacher-reported co-occurring problems relative to all other groups through greater early childhood negative affectivity. Lower levels of the aggression PRS and higher levels of the internalizing PRS indirectly predicted co-occurring problems relative to the externalizing "only" and low problem groups (primary caregivers only) through greater early childhood behavioral inhibition. Findings suggest two different genetic pathways to co-occurring problems that could lead to distinct prevention and intervention efforts. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415528 | PMC |
| http://dx.doi.org/10.1037/abn0000525 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effectiveness comparison of an indicated child-centered group prevention program for disruptive behavior problems in children with vs. without co-occurring emotional problems.
BMC Psychol
September 2025
Behavioral Epidemiology, Institute of Clinical Psychology and Psychotherapy, TUD Dresden University of Technology, Chemnitzer Straße 46, 01187, Dresden, Germany.
Background: Disruptive behavior and emotional problems - especially anxiety - are common in children and frequently co-occur. However, the role of co-occurring emotional problems in disruptive behavior intervention response is unclear. This study aimed to compare the effectiveness of an indicated prevention program in children with disruptive behavior problems with vs.
View Article and Find Full Text PDF[Type D personality style and back pain : A narrative overview of the relevance of psychosocial factors in orthopedic pain therapy].
Orthopadie (Heidelb)
September 2025
Orthopädische Universitätsklinik Magdeburg, Medizinische Fakultät, Otto-von-Guericke-Universität Magdeburg, Magdeburg, Deutschland.
Background: The Type D personality ("distressed personality") is characterized by a combination of negative affectivity and social inhibition. While this personality style was originally researched in the context of cardiovascular disease, recent studies also show a significant association with chronic pain disorders, especially back pain.
Objectives: This narrative review examines the current state of knowledge on the relationship between type D personality and back pain.
The Role of Worry and Affectivity on Physiological Responses To an Acute Stressor.
Appl Psychophysiol Biofeedback
September 2025
Florida State University, Tallahassee, USA.
The explanation for how acutely stressful experiences could result in proximal health outcomes has been lacking in occupational health research. Although scholars have argued that individual personality and affect could worsen health behaviors, we believe that these qualities also could intensify the experience of acute stressors, potentially explaining why acutely stress encounters result in poor health outcomes for some people, but not others. Our study examines three individual differences - worry, negative affect, and positive affect - that are relevant to differential stress anticipation, reactivity, and recovery.
View Article and Find Full Text PDFDevelopment, and pilot study of a single-session 'Intervention for Caregiver Affiliate stigma REduction' (i-CARE) in a tertiary care specialty psychiatry setting in North India for severe mental illnesses.
Indian J Psychiatry
August 2025
Department of Clinical Psychology, Institute of Human Behaviour and Allied Sciences, Delhi, India.
Background: Affiliate stigma (AS) is self-stigma in caregivers, having three salient components: affective, behavioral, and cognitive. High caregiver AS causes concealment of mental illness and has negative consequences. Appropriate intervention for AS can offset such consequences.
View Article and Find Full Text PDFAssociations between psychotic experience dimensions and polygenic liability to schizophrenia in a longitudinal birth cohort.
BJPsych Open
September 2025
Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Population Health Sciences, Bristol Medical School, Bristol, UK.
Background: Some psychotic experiences in the general population show associations with higher schizophrenia and other mental health-related polygenic risk scores (PRSs), but studies have not usually included interviewer-rated positive, negative and disorganised dimensions, which show distinct associations in clinical samples.
Aims: To investigate associations of these psychotic experience dimensions primarily with schizophrenia PRS and, secondarily, with other relevant PRSs.
Method: Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort participants were assessed for positive, negative and disorganised psychotic experience dimensions from interviews, and for self-rated negative symptoms, at 24 years of age.