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http://dx.doi.org/10.1542/pir.2019-0103 | DOI Listing |
Endocrinol Diabetes Metab Case Rep
July 2025
Department of Internal Medicine, Medical City Arlington, Arlington, Texas, USA.
Summary: Hypercalcemia is a prevalent electrolyte disturbance commonly associated with primary hyperparathyroidism, cancer, or medication adverse effects. Thiazide diuretics reduce urinary calcium excretion, increasing calcium reabsorption and hypercalcemia. Tirzepatide, a dual GIP and GLP-1 receptor agonist, is increasingly used for type 2 diabetes and obesity.
View Article and Find Full Text PDFFront Med (Lausanne)
August 2025
Department of Endocrinology, Chengdu Shuangliu Hospital of Traditional Chinese Medicine, Chengdu, China.
Objectives: The association between SARS-CoV-2 infection and endocrine emergencies (such as fulminant type 1 diabetes mellitus and subacute thyroiditis) has received increasing attention. However, concurrent manifestations of these two conditions within a short period of time after infection are exceedingly rare, and the underlying mechanisms and clinical management strategies remain unclear.
Case Presentation: A 45-year-old Chinese man developed sudden polydipsia, polyuria, and cervical pain on day 7, within 2 weeks of SARS-CoV-2 infection.
Cureus
August 2025
General Internal Medicine and Nephrology, Robert Bosch Krankenhaus, Stuttgart, DEU.
Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare autoimmune condition primarily affecting adolescents. Diagnosis is frequently delayed due to the nonspecific and temporally dissociated presentation of renal and ocular symptoms. We report the case of a 15-year-old girl who presented to her general practitioner with fatigue, polyuria, and recent weight loss.
View Article and Find Full Text PDFIndian J Nephrol
July 2024
Department of Nephrology, Institute of Nephro-Urology, Bangalore, Karnataka, India.
A 30-year-old male born from a consanguineous marriage, with intellectual disability, developmental delay and Type 1 diabetes presented with polyuria and uremic symptoms. Physical examination revealed hypertension, retinitis pigmentosa, bilateral rotatory grade 3 nystagmus, eyelid droop, truncal obesity, acanthosis nigricans, and muscle hypotonia. Laboratory tests indicated kidney dysfunction.
View Article and Find Full Text PDFClin Case Rep
September 2025
Department of Embryology, Faculty of Medicine University of Thessaly Larissa Greece.
Bartter syndrome is an idiopathic condition that may manifest antenatally, characterized by a spectrum of symptoms including maternal polyhydramnios, prematurity, polyuria, hypercalciuria, nephrocalcinosis, normomagnesemia, vomiting, growth retardation, and elevated renal synthesis and urinary excretion of prostaglandins. Herein, we present a case of a 36-year-old Caucasian woman (Gravida 1, Para 0) diagnosed with extensive hydramnios at the 27th week of gestation. A decision for decompressive amniocentesis was made, and the amniotic fluid was sent for biochemical testing.
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