98%
921
2 minutes
20
Study Design: Retrospective cohort study.
Objectives: To assess how the thoracic kyphosis affects the ability of the fulcrum bending radiograph (FBR) to predict the coronal thoracic curve correction.
Methods: A retrospective study of prospectively collected data was conducted of 107 consecutive patients with thoracic adolescent idiopathic scoliosis (AIS) treated with a standard screw-fixation protocol. Radiographic variables were assessed preoperatively and at 2-year follow-up. Curve flexibility was determined based on the FBR and the Fulcrum Bending Flexibility Index (FBCI). Radiographic variables included preoperative Cobb angle, T5-T12 kyphosis, T12-S1 lordosis, sagittal vertical axis, list, T1-T12 length, truncal shift, and radiographic shoulder height. Patients were also categorized as hypo-, normo-, or hyperkyphotic.
Results: Based on multivariate modeling, an increase in FBR Cobb angle and thoracic kyphosis were significantly associated with an increase in FBCI (increased mismatch between the FBR and postoperative Cobb angles) at 2-year follow-up ( < 0.001). In patients with hyperkyphosis, a longer instrumented length existed despite similar curve size and shorter curve length than the hypo- and normokyphotic groups. Based on these findings, we developed a new predictive postoperative curve correction index, known as the Multiprofile Flexibility Index (MFI).
Conclusions: Our results show that an increase in preoperative thoracic kyphosis is associated with an increased difference between the preoperative coronal curve flexibility and the postoperative coronal curve correction. Our findings broaden the understanding of curve flexibility and indicate that selection of fusion levels may need to take into consideration the sagittal profile to improve clinical decision making and optimize outcome.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160813 | PMC |
http://dx.doi.org/10.1177/2192568219877862 | DOI Listing |
Prog Mol Biol Transl Sci
September 2025
Department of Systems and Computer Engineering, Carleton University, Ottawa, ON, Canada. Electronic address:
Monitoring skeletal muscle contraction provides valuable information about the muscle mechanical properties, which can be helpful in various biomedical applications. This chapter presents a single-element flexible and wearable ultrasonic sensor (WUS) developed by our research group and its application for continuously monitoring and characterizing skeletal muscle contraction. The WUS is made from a 110-µm thick polyvinylidene fluoride piezoelectric polymer film.
View Article and Find Full Text PDFJ Thermoplast Compos Mater
August 2025
Institute for Applied Materials - Microstructure Modeling and Simulation, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
In this paper, we introduce a coarse-grained model of polymer crystallization using a multiphase-field approach. The model combines a multiphase-field method, Nakamura's kinetic equation, and the equation of heat conduction for studying microstructural evolution of crystallization under isothermal and non-isothermal conditions. The multiphase-field method provides flexibility in adding any number of phases with different properties making the model effective in studying blends or composite materials.
View Article and Find Full Text PDFNanotechnology
September 2025
State Key Laboratory of Optoelectronic Materials and Technologies School of Chemistry and Chemical Engineering, Sun Yat-Sen University, No 135, XinGangXi Road, Guangzhou 510275, guangzhou, 510275, CHINA.
Silicon carbide nanowires (SiC NWs) combine the benefits of bulk SiC materials with the properties of low-dimensional nanomaterials. They are known for their excellent mechanical strength and durability, which are critical for their potential applications in high-stress environments and micro-nano functional systems. Here, the mechanical properties and deformation mechanisms of 2H-SiC NWs with rare defects in the [0001] orientation are reported.
View Article and Find Full Text PDFAnal Biochem
September 2025
Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, 4-101 Koyama-Cho Minami, Tottori, 680-8552, Japan.
The duplex-forming behavior of an inchworm-type PNA-PEG conjugate (i-PPc), engineered for the selective recognition of point mutations in DNA, was assessed through thermodynamic analysis employing UV melting curves and circular dichroism spectroscopy. The i-PPc demonstrated the ability to form stable duplexes exclusively with fully complementary DNA sequences, while no hybridization with single-base mismatched sequences. This binary on/off hybridization behavior was maintained even under physiologically relevant conditions (37 °C), thereby illustrating the exceptional point mutation discrimination capability of i-PPc.
View Article and Find Full Text PDFCarbohydr Polym
November 2025
Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industry Microbiology, Hubei University of Technology, Wuhan 430068, China. Electronic address:
The polyunsaturated fatty acids in fish oil are prone to oxidation and have poor dispersibility, which limits their use in the food sector. In this work, oil-in-water emulsions stabilized by chitin nanocrystals (ChNC) were prepared via high-speed homogenization. Anionic carboxymethyl cellulose (CMC) was assembled onto cationic ChNC-stabilized emulsion droplet surfaces via layer-by-layer self-assembly technology to construct ChNC/CMC (Ch-C) bilayer emulsions with rigid inner layer and flexible outer shell structures.
View Article and Find Full Text PDF