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Amidst the considerable attention artificial intelligence (AI) has attracted in recent years, a neuromorphic chip that mimics the biological neuron has emerged as a promising technology. Memristor or Resistive random-access memory (RRAM) is widely used to implement a synaptic device. Recently, 3D vertical RRAM (VRRAM) has become a promising candidate to reducing resistive memory bit cost. This study investigates the operation principle of synapse in 3D VRRAM architecture. In these devices, the classification response current through a vertical pillar is set by applying a training algorithm to the memristors. The accuracy of neural networks with 3D VRRAM synapses was verified by using the HSPICE simulator to classify the alphabet in 7×7 character images. This simulation demonstrated that 3D VRRAMs are usable as synapses in a neural network system and that a 3D VRRAM synapse should be designed to consider the initial value of the memristor to prepare the training conditions for high classification accuracy. These results mean that a synaptic circuit using 3D VRRAM will become a key technology for implementing neural computing hardware.
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http://dx.doi.org/10.1166/jnn.2020.17798 | DOI Listing |
Neurology
October 2025
Alzheimer's Disease and Other Cognitive Disorders Unit, Department of Neurology, Hospital Clínic de Barcelona, Fundació Recerca Clínic Barcelona-IDIBAPS, Spain.
Background And Objectives: α-Synuclein seed amplification assays (αSAAs) can improve the diagnosis of synucleinopathies and detect α-synuclein (αSyn) copathology in vivo in clinical practice. We aimed to evaluate the diagnostic performance of αSAA for detecting αSyn in CSF for diagnosing dementia with Lewy bodies (DLB) in a clinical cohort of cognitively impaired individuals. We explored how the coexistence of Alzheimer disease (AD) and αSyn pathology influences biomarker levels and clinical profiles.
View Article and Find Full Text PDFPLoS One
September 2025
College of Information Engineering, Sichuan Agricultural University, Ya'an, Sichuan Province, China.
Animals communicate information primarily via their calls, and directly using their vocalizations proves essential for executing species conservation and tracking biodiversity. Conventional visual approaches are frequently limited by distance and surroundings, while call-based monitoring concentrates solely on the animals themselves, proving more effective and straightforward than visual techniques. This paper introduces an animal sound classification model named SeqFusionNet, integrating the sequential encoding of Transformer with the global perception of MLP to achieve robust global feature extraction.
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September 2025
Korea University College of Medicine, Seoul, Republic of Korea.
Purpose: To develop and validate a deep learning-based model for automated evaluation of mammography phantom images, with the goal of improving inter-radiologist agreement and enhancing the efficiency of quality control within South Korea's national accreditation system.
Materials And Methods: A total of 5,917 mammography phantom images were collected from the Korea Institute for Accreditation of Medical Imaging (KIAMI). After preprocessing, 5,813 images (98.
PLOS Digit Health
September 2025
Department of Dermatology, Stanford University, Stanford, California, United States of America.
Large Language Models (LLMs) are increasingly deployed in clinical settings for tasks ranging from patient communication to decision support. While these models demonstrate race-based and binary gender biases, anti-LGBTQIA+ bias remains understudied despite documented healthcare disparities affecting these populations. In this work, we evaluated the potential of LLMs to propagate anti-LGBTQIA+ medical bias and misinformation.
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September 2025
Smart Manufacturing and Artificial Intelligence, Micron Memory Malaysia Sdn. Bhd., Batu Kawan, Penang, Malaysia.
Advances in data collection have resulted in an exponential growth of high-dimensional microarray datasets for binary classification in bioinformatics and medical diagnostics. These datasets generally possess many features but relatively few samples, resulting in challenges associated with the "curse of dimensionality", such as feature redundancy and an elevated risk of overfitting. While traditional feature selection approaches, such as filter-based and wrapper-based approaches, can help to reduce dimensionality, they often struggle to capture feature interactions while adequately preserving model generalization.
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