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Objective: This study investigated the effect of 3 weeks of high-sugar ("Sweet") versus low-sugar ("Plain") breakfast on energy balance, metabolic health, and appetite.
Methods: A total of 29 healthy adults (22 women) completed this randomized crossover study. Participants had pre- and postintervention appetite, health, and body mass outcomes measured, and they recorded diet, appetite (visual analogue scales), and physical activity for 8 days during each intervention. Interventions were 3 weeks of isoenergetic Sweet (30% by weight added sugar; average 32 g of sugar) versus Plain (no added sugar; average 8 g of sugar) porridge-based breakfasts.
Results: Pre- to postintervention changes in body mass were similar between Plain (Δ 0.1 kg; 95% CI: -0.3 to 0.5 kg) and Sweet (Δ 0.2 kg; 95% CI: -0.2 to 0.5 kg), as were pre- to postintervention changes for biomarkers of health (all P ≥ 0.101) and psychological appetite (all P ≥ 0.152). Energy, fat, and protein intake was not statistically different between conditions. Total carbohydrate intake was higher during Sweet (287 ± 82 g/d vs. 256 ± 73 g/d; P = 0.009), driven more by higher sugar intake at breakfast (116 ± 46 g/d vs. 88 ± 38 g/d; P < 0.001) than post-breakfast sugar intake (Sweet 84 ± 42 g/d vs. Plain 80 ± 37 g/d; P = 0.552). Participants reported reduced sweet desire immediately after Sweet but not Plain breakfasts (trial × time P < 0.001).
Conclusions: Energy balance, health markers, and appetite did not respond differently to 3 weeks of high- or low-sugar breakfasts.
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http://dx.doi.org/10.1002/oby.22757 | DOI Listing |
Wounds
August 2025
Faculty of Physical Therapy, Cairo University, Cairo, Giza, Egypt.
Background: Charcot foot is a debilitating complication of peripheral neuropathy and is primarily associated with diabetes, leading to structural damage, ulceration, and osteomyelitis. Pulsed electromagnetic field (PEMF) therapy is a promising treatment modality for wound healing and bone metabolism.
Objective: To evaluate the efficacy of PEMF therapy in promoting bone growth and ulcer healing in patients with Charcot foot ulcers.
J Gen Intern Med
September 2025
University of Colorado School of Medicine, 1890 N Revere Ct, Third Floor, Mail Stop F443, Aurora, CO, 80045, USA.
Background: The SHARE Approach Model and training curriculum was developed by the Agency for Healthcare Research and Quality (AHRQ) to teach clinicians practicing in diverse settings how to engage in more effective Shared Decision Making (SDM).
Objective: To determine the effectiveness of the SHARE Approach at improving SDM in practices located across Colorado, USA.
Design: A longitudinal study with pre- and post-intervention observations.
J Affect Disord
September 2025
Department of Psychology, Florida State University, 1107 W Call St., Tallahassee, FL 32304, USA.
Active-duty military personnel often face significant mental health challenges, including high rates of anxiety, depression, and substance abuse. Despite the clear need for mental health interventions, service members frequently underutilize available services due to time constraints, concerns about career impact, and confidentiality issues. This study evaluates the acceptability and clinical impact of the Health Education Training (HET) program, a 50-min, single-session, computer-based intervention designed to promote healthy lifestyle behaviors among active-duty military personnel.
View Article and Find Full Text PDFHum Reprod
September 2025
Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.
Study Question: Does weight loss from a hypocaloric dietary intervention improve antral follicle dynamics in women with PCOS?
Summary Answer: During a 3-month hypocaloric dietary intervention, women with PCOS who experienced clinically meaningful weight loss showed more organized antral follicle development including fewer recruitment events, but no change in the overall frequency of selection, dominance, or ovulation.
What Is Known Already: There is a spectrum of disordered antral follicle development in women with PCOS including excessive follicle recruitment and turnover, decreased frequency of selection and dominance, and failure of ovulation. Lifestyle intervention aimed at weight loss is recommended to improve metabolic health in women with PCOS yet benefits on ovarian follicle development and ovulation are unclear.
Front Med (Lausanne)
August 2025
Department of Health Sciences, University of York, York, United Kingdom.
Introduction: Simulation-Based Teaching (SBT) has emerged as an educational strategy to enhance clinical competence among medical students, particularly in Gynaecology and Obstetrics.
Objective: This study assessed the effectiveness of learning SBT and explored the enablers and challenges associated with implementing SBT in Gynaecology and Obstetrics.
Methods: Using a sequential explanatory mixed methods approach a study was conducted in Skills Lab at Pakistan Emirates Military Hospital (PEMH), Rawalpindi during May-Sep 2024.