Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Introduction: There is growing evidence that mental disorders behave like complex dynamic systems. Complex dynamic systems theory states that a slower recovery from small perturbations indicates a loss of resilience of a system. This study is the first to test whether the speed of recovery of affect states from small daily life perturbations predicts changes in psychopathological symptoms over 1 year in a group of adolescents at increased risk for mental disorders.

Methods: We used data from 157 adolescents from the TWINSSCAN study. Course of psychopathology was operationalized as the 1-year change in the Symptom Checklist-90 sum score. Two groups were defined: one with stable and one with increasing symptom levels. Time-series data on momentary daily affect and daily unpleasant events were collected 10 times a day for 6 days at baseline. We modeled the time-lagged effect of daily unpleasant events on negative and positive affect after each unpleasant event experienced, to examine at which time point the impact of the events is no longer detectable.

Results: There was a significant difference between groups in the effect of unpleasant events on negative affect 90 min after the events were reported. Stratified by group, in the Increase group, the effect of unpleasant events on both negative (B = 0.05, p < 0.01) and positive affect (B = - 0. 08, p < 0.01) was still detectable 90 min after the events, whereas in the Stable group this was not the case.

Conclusion: Findings cautiously suggest that adolescents who develop more symptoms in the following year may display a slower affect recovery from daily perturbations at baseline. This supports the notion that mental health may behave according to the laws of a complex dynamic system. Future research needs to examine whether these dynamic indicators of system resilience may prove valuable for personalized risk assessment in this field.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027206PMC
http://dx.doi.org/10.1186/s12916-020-1500-9DOI Listing

Publication Analysis

Top Keywords

unpleasant events
16
events negative
12
daily life
8
complex dynamic
8
dynamic systems
8
daily unpleasant
8
events
6
affect
5
daily
5
unpleasant
5

Similar Publications

Activation of Locus Coeruleus-Hippocampus Tyrosine Hydroxylase Projection Contributes to the Surgical Incision Pain-Induced Memory Consolidation Enhancement in Mice.

CNS Neurosci Ther

September 2025

Department of Anaesthesiology, The First Affiliated Hospital of Anhui Medical University, Key Laboratory of Anaesthesia and Perioperative Medicine of Anhui Higher Education Institutes, Anhui Medical University, Hefei, China.

Aims: The mechanism underlying postoperative post-traumatic stress disorder (PTSD) remains unclear. However, studies have shown that acute postoperative pain is an independent risk factor for PTSD, which is also closely related to memory consolidation enhancement. Preoperative patients often experience unpleasant traumatic events, and postoperative pain usually occurs in the memory consolidation stage of these events.

View Article and Find Full Text PDF

Prolonging Medical Procedures to Exploit the Peak-End Rule: An Ethical Analysis.

J Eval Clin Pract

September 2025

Academic Unit of Population and Lifespan Sciences, School of Medicine, University of Nottingham, Clinical Sciences Building, Nottingham City Hospital Campus, Nottingham, UK.

Introduction: The Peak-End Rule (PER) impacts how individuals remember events: experiences are primarily remembered according to the emotions associated with the experience's most intense moment (the peak) and those associated with its end (the end). The potential utility of exploiting the PER for improving patients' willingness to repeat unpleasant but medically useful procedures in the future has been demonstrated.

Methods: This paper conducts an analysis of the ethical issues surrounding the prolongation of medical procedures to exploit the PER.

View Article and Find Full Text PDF

Background/objectives: Neuromodulation is under investigation as a possibly effective add-on therapy in Alzheimer's disease (AD). While transcranial pulse stimulation (TPS) has shown positive short-term effects, long-term effects have not yet been fully explored. This study aims to evaluate the long-term feasibility, safety, and potential cognitive benefits of TPS over one year in patients with Alzheimer's disease, focusing on domains such as memory, speech, orientation, visuo-construction, and depressive symptoms.

View Article and Find Full Text PDF

Controlling unwanted memories: A conceptual review grounded in the process model of emotion regulation.

Psychon Bull Rev

August 2025

School of Psychology, The University of Sydney, Brennan MacCallum Building A18, Sydney, NSW, 2006, Australia.

Autobiographical memories are a crucial source of emotional states in our daily lives. While remembering negative events in the past is important to guide future behaviours and steer us away from harm, being reminded of unpleasant events too often or too intensely can have a serious impact on our wellbeing. A solution that may reconcile these positive and negative effects of negative memories is memory control.

View Article and Find Full Text PDF

Misophonia is a condition typically described as heightened intolerance to specific everyday sounds, although intense emotional and physiological responses can also be triggered by non-auditory representations of the sources of these sounds, e.g., words, videos, or imagination (Swedo et al.

View Article and Find Full Text PDF