98%
921
2 minutes
20
Objective: To quantify how a control software upgrade changed beam delivery times and impacted efficiency and capacity of a multiroom proton therapy center.
Methods: A four-room center treating approximately 90 patients/day, treating for approximately 7 years with optimized operations, underwent a software upgrade which reduced room and energy switching times from approximately 30 to 20 s and approximately 4 s to ~0.5 s, respectively. The center uses radio-frequency identification data to track patient treatments and has software which links this to beam delivery data extracted from the treatment log server. Two 4-month periods, with comparable patient volume, representing periods before and after the software change, were retrospectively analyzed.
Results: A total of 16,168 and 17,102 fields were analyzed. For bilateral head and neck and prostate patients, the beam waiting time was reduced by nearly a factor of 3 and the beam delivery times were reduced by nearly a factor of 2.5. Room switching times were reduced more modestly. Gantry capacity has increased from approximately 30 patients to 40-45 patients in a 16-h daily operation.
Conclusions: Many proton centers are striving for increased efficiencies. We demonstrated that reductions in energy and room switching time can significantly increase center capacity. Greater potential for further gains would come from improvements in setup and imaging efficiency.
Advances In Knowledge: This paper provides detailed measured data on the effect on treatment times resulting from reducing energy and room switching times under controlled conditions. It helps validate the models of previous investigations to establish treatment capacity of a proton therapy center.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066962 | PMC |
http://dx.doi.org/10.1259/bjr.20190820 | DOI Listing |
World J Pediatr Congenit Heart Surg
September 2025
Department of Cardiology, Boston Children's Hospital, Boston, MA, USA.
There is a paucity of data available regarding operative timing and approach for d-loop transposition of the great arteries (dTGA) with intact ventricular septum (IVS) in premature infants. We reviewed our surgical experience in a case series of five premature infants (<37 weeks gestational age) with dTGA/IVS and birthweights <2.0 kg.
View Article and Find Full Text PDFAdv Mater
September 2025
Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, 100190, China.
Atomically thin 2D layered ferroelectric semiconductors, where polarization switching transpires within the channel material itself, are pivotal to advancing the next generation of high-performance electronics. Nevertheless, the challenge remains in either the controllable synthesis of films or the manipulation of associated ferroelectricity. Here, 2D p-type BiCuSeO (BCSO) films with a thickness down to ≈3 nm are successfully synthesized using molecular beam epitaxy.
View Article and Find Full Text PDFJ Cataract Refract Surg
September 2025
Radboud university medical center, Department of Intensive Care Medicine, Nijmegen, the Netherlands.
Purpose: The healthcare sector significantly contributes to environmental challenges. Cataract surgery, as one of the most frequently performed procedures worldwide, presents an opportunity to address these challenges. This study identifies the main environmental hotspots of cataract surgery and evaluates strategies to reduce its environmental impact.
View Article and Find Full Text PDFNanoscale
September 2025
Department of Physics, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.
Memristors have emerged as promising candidates for high-density non-volatile memory and neuromorphic computing due to their simple structure and low power operation. However, conventional memristive switching devices often require a lot of energy for fabrication processes and high operating voltages, which not only hinder integration with flexible substrates but also impose substantial limitations on overall energy efficiency. In this study, we demonstrated a memristive switching device based on copper sulfide (CuS), fabricated through a room-temperature sulfurization synthesis process.
View Article and Find Full Text PDFACS Nano
August 2025
Electrical and Computer Engineering Department, University of Michigan; Ann Arbor, Michigan 48109-2122, United States.
The efficiency of most electronic devices is limited by scattering and capacitive losses among purely electronic processes. Charge-neutral excitons could reduce both losses and, thus, offer more efficient switching pathways. However, it remains challenging to achieve exciton transport that is fast, guided, and unidirectional enough for gating processes.
View Article and Find Full Text PDF