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http://dx.doi.org/10.1007/s11427-019-1561-1 | DOI Listing |
BMC Pregnancy Childbirth
September 2025
Department of General Practice, Institute of Clinical Medicine, University of Turku and Turku University Hospital, Turun Yliopisto, Yleislääketiede, 20014 Turun Yliopisto, Turku, Finland.
Background: A strong parental (maternal/ paternal)-fetal attachment predicts a stronger parental-infant attachment after the child is born. An unintended pregnancy has been associated with weakened development of a maternal-fetal attachment. However, the knowledge of association between an unintended pregnancy and the development of a paternal-fetal attachment is scarce.
View Article and Find Full Text PDFNucleic Acids Res
August 2025
Institute of Molecular Biology, Academia Sinica, Taipei 11529, Taiwan.
Rad51 and meiosis-specific Dmc1 catalyze homologous recombination (HR) between maternal and paternal chromosomes during meiosis in many sexual eukaryotes, generating three interhomolog (IH) recombination products: non-crossovers (NCOs), class I interference-sensitive crossovers (COs), and class II non-interfering COs. CO interference suppresses relatively close CO formation. Some COs form chiasmata, which physically connect homologous chromosomes and ensure proper chromosome segregation during meiosis I.
View Article and Find Full Text PDFCureus
August 2025
Obstetrics and Gynecology, Salmaniya Medical Complex, Manama, BHR.
Background Gestational trophoblastic disease (GTD) refers to a group of conditions linked to abnormal growth of trophoblastic tissue following conception. Although uncommon, early detection of GTD is vital due to the potential for progression and serious complications. The prevalence and presentation of GTD vary by region.
View Article and Find Full Text PDFNucleic Acids Res
August 2025
Roche Pharma Research and Early Development, Neuroscience and Rare Disease discovery and translational area, Roche Innovation Center Basel, Basel 4070, Switzerland.
Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by the loss of neuronal ubiquitin E3 ligase UBE3A, with no available treatment. Restoring UBE3A by downregulating the paternally cis-acting long noncoding antisense transcript (UBE3A-ATS) is a potentially disease modifying strategy. However, developing molecules targeting human UBE3A-ATS is challenging due to its selective expression in mature neurons and lack of sequence conservation across species.
View Article and Find Full Text PDFPlants (Basel)
August 2025
Forest Tree Genetics and Breeding Laboratory, College of Forestry, Hebei Agricultural University, Baoding 071001, China.
With the increasing severity of forest pest problems, breeding insect-resistant varieties has become a crucial task for the sustainable development of forestry. The highly insect-resistant triploid Populus line Pb29, genetically modified with , served as the maternal parent in controlled hybridization with three paternal Populus cultivars. Hybrid progenies were obtained through embryo rescue and tissue culture.
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