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Hormones are known to influence various body systems that include skeletal, cardiac, digestive, excretory, and immune systems. Emerging investigations suggest the key role played by secretions of endocrine glands in immune cell differentiation, proliferation, activation, and memory attributes of the immune system. The link between steroid hormones such as glucocorticoids and inflammation is widely known. However, the role of peptide hormones and amino acid derivatives such as growth and thyroid hormones, prolactin, dopamine, and thymopoietin in regulating the functioning of the immune system remains unclear. Here, we reviewed the findings pertinent to the functional role of hormone-immune interactions in health and disease and proposed perspective directions for translational research in the field.
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http://dx.doi.org/10.2174/1389203720666191106113435 | DOI Listing |
BMC Emerg Med
September 2025
Department of Neurology and Clinical Neuroscience, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Background: Identifying suspected anterior circulation large-vessel occlusion (aLVO) strokes during emergency calls could enhance dispatch efficiency, particularly in rural areas. However, data on emergency medical dispatchers' (EMDs) ability to recognize aLVO symptoms remain limited. This simulation study aimed to evaluate the feasibility of identifying side-specific arm paresis, side-specific conjugate eye deviation (CED), and aphasia during emergency calls by instructing layperson callers to perform brief, standardized examination steps.
View Article and Find Full Text PDFBMC Biotechnol
September 2025
Faculty of Science, Department of Biotechnology and Food Technology, University of Johannesburg, P.O. Box 17011, Doornfontein, Johannesburg, Gauteng, 2028, South Africa.
Patulin (PAT), a mycotoxin produced primarily by Penicillium expansum, poses significant health risks and frequently contaminates apples and apple-derived products, often exceeding permissible safety limits. This study investigated the potential of orotate phosphoribosyl transferase (URA5) to degrade PAT in apple juice under controlled conditions. PAT degradation was assessed at initial concentrations of 100 µg/L and 250 µg/L, with enzymatic treatment using 0.
View Article and Find Full Text PDFBMC Med Inform Decis Mak
September 2025
Emergency Department, Helios Spital, Überlingen, Germany.
Background: The increasing amount of data routinely collected on ICUs poses a challenge for clinicians which is aggravated with data-heavy therapies like Continuous Kidney Replacement Therapy (CKRT). We developed the CKRT Supporting Software Prototype (CKRT-SSP), a clinical decision support system for use before, during and after CKRT. The aim of this user experience (UX) study was to prospectively evaluate CKRT-SSP in terms of usability, user experience, and workload in a simulated ICU setting.
View Article and Find Full Text PDFJ Behav Health Serv Res
September 2025
Department of Counselor Education, Fairfield University, Fairfield, CT, USA.
This qualitative study explores what factors influence teaming in behavioral health settings, from the perspective of behavioral health providers. Twenty-four participants from a range of behavioral health professions engaged in semi-structured interviews. Using a grounded theory approach, data were analyzed, and a "prism" model was developed to capture the complexities of behavioral health providers' perceptions of factors influencing teaming in various mental health and/or substance use disorder treatment programs.
View Article and Find Full Text PDFJ Neural Transm (Vienna)
September 2025
Department of Clinical and Health Psychology, University of Vienna, Liebiggasse 5, Vienna, 1010, Austria.
Tiredness may be associated with increased or decreased sexual experience and behavior while fatigue seems to have a predominantly negative effect, although evidence is scarce. This ecological momentary assessment study is the first to examine associations between tiredness or fatigue and concurrent / subsequent sexual desire or sexual arousal and previous / subsequent sexual activity in daily life, including event-based measurements and considering gender differences. Healthy heterosexual individuals (n = 63), aged between 19 and 32 years and in a relationship, indicated their tiredness, general fatigue, physical fatigue, sexual desire, and sexual arousal on an iPod seven times daily over 14 days, and any event-based occurrences of sexual activity.
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