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Introduction: First tarsometatarsal (TMT) joint fusion is routinely used for arthritis and deformities. Common fixation methods include a locking plate construct, cross-screws, or combinations of the two. Cross screws have proven effective for union and stability; however, there is a potential for harm to nearby neurovascular structures due to the nature of percutaneous insertion technique. This study assessed risk of damage to the superficial peroneal nerve with percutaneous TMT fusion.
Methods: Nine fresh-frozen cadaver specimens were included. A medial incision in the internervous plane was made for TMT joint preparation. Two crossed percutaneous wires followed by 4.0 cc screws were placed in the dorsal aspect of the proximal aspect of first metatarsal and in the medial cuneiform. Both were 10-15 mm from the TMT joint line. The dorsal aspect of the foot was dissected and examined for neurovascular interruptions, particularly branches of the superficial peroneal nerve.
Results: Results showed a mean distance of 4.33 mm from the proximal pin to the medial branch of the superficial peroneal nerve. The distal pin had a mean distance of 6.44 mm from the medial branch, with one pin 9 mm from the lateral branch. One incident of direct injury to the neurovascular bundle was observed.
Conclusion: Preparing the joint from the medial side using a percutaneous approach is less invasive, but presents a relative risk for neuritis. Care should be taken during insertion of the percutaneous screw after TMT joint preparation for fusion.
Level Of Evidence: Level V, cadaver study.
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http://dx.doi.org/10.1016/j.foot.2019.05.006 | DOI Listing |
Alzheimers Dement
September 2025
Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Introduction: Plasma biomarkers' utility for predicting incident mild cognitive impairment (MCI) remains unclear. We evaluated associations of plasma Alzheimer's disease (AD) biomarkers and amyloid positron emission tomography (PET) with transitions from cognitively unimpaired (CU) to MCI in the Mayo Clinic Study of Aging (MCSA) and BioFINDER-2 studies.
Methods: Associations of continuous baseline plasma biomarker levels and amyloid PET Centiloid with progression to MCI, adjusting for age, sex, and education, were evaluated with Cox proportional hazards models.
Sci Data
July 2025
Division of Biomechanics and Research Development, Department of Biomechanics, and Center for Research in Human Movement Variability, University of Nebraska at Omaha, Omaha, NE 68182, USA.
We present a publicly available dataset, offering annotated full-body kinematics, gaze tracking, and ground reaction forces and moments from 48 healthy young adults performing a life-size suprapostural task. Using a 12-camera motion capture system, eye tracker, and force plate, we recorded full-body kinematics, eye gaze and pupil diameter, and ground reaction forces and moments as participants completed four tasks: standing upright, performing the Trail Making Test (TMT) Part A projected on a screen using a laser pointer and repeating these conditions on a wobble board inducing instability along the mediolateral axis. Each trial lasted five minutes, and the total number of trail connections was recorded.
View Article and Find Full Text PDFZhejiang Da Xue Xue Bao Yi Xue Ban
July 2025
Department of Pharmacy, the 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Key Laboratory of Plateau Medicine, Lanzhou 730050, China.
Objectives: To investigate the targets and mechanisms of 7-hydroxyethyl chrysin (7-HEC) in prevention and treatment of high-altitude cerebral edema (HACE) in rats.
Methods: Fifty-four male Wistar rats were randomly divided into normal control group, HACE model group, and 7-HEC-treated group (18 rats in each group). Except for the normal control group, rats in the two other groups were exposed to a hypobaric hypoxic chamber simulating a 7000 m altitude for 72 h to establish the HACE model.
Foot Ankle Int
July 2025
Seoul Foot and Ankle Center, Dubalo Orthopaedic Clinic, Seoul, Republic of Korea.
Background: Progressive collapsing flatfoot deformity (PCFD) has been reported as a common cause of the nontraumatic degenerative arthritis of the midfoot, and arthrodesis has been used for symptomatic arthritis unresponsive to nonoperative measures. The hypothesis of this study was that nontraumatic central tarsometatarsal (TMT) arthritis associated with PCFD would be improved without arthrodesis by restoration of medial longitudinal arch. The aim of this study was to investigate the clinical and radiologic results of central TMT arthritis with medial longitudinal arch restoration in PCFD.
View Article and Find Full Text PDFFoot Ankle Int
August 2025
Guangdong Provincial Key Laboratory of Digital Medicine and Biomechanics & Guangdong Engineering Research Center for Translation of Medical 3D Printing Application, Guangzhou, Guangdong, China.
Background: Plantar displacement during chevron osteotomy may improve load distribution in hallux valgus, but biomechanical evidence is limited. This study evaluates how lateral and plantar displacement affect contact properties in the first metatarsophalangeal (MTP-1) and the first tarsometatarsal (TMT-1) joints under standing load.
Methods: Twelve cadaveric feet with hallux valgus and 4 normal specimens were tested under simulated standing load.