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cells can mount a number of responses to nutritional deprivation but ultimately either form dormant spores or enter a metabolically quiescent state. In a recent article (mBio 10:e01414-19, https://doi.org/10.1128/mBio.01414-19, 2019), R. Hashuel and S. Ben-Yehuda report on a novel means by which nutrient-starved cells escape from aging (days-old) colonies by accumulating mutations enabling them to continue growth under nutrient-limited conditions. They postulate that such a strategy may be a major factor determining the dynamics of bacterial populations in natural environments.
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http://dx.doi.org/10.1128/mBio.02461-19 | DOI Listing |
Adv Healthc Mater
July 2025
Department of Chemical Engineering and Materials Science, Ewha Womans University, Seoul, 03760, Republic of Korea.
Conformal skin-electrode contact is crucial for acquiring high-quality multimodal biosignals from the uneven human epidermis. Although stretchable dry adhesives (SDAs) are promising solutions, their development is hindered by the low stretchability and high hygroscopicity of biocompatible adhesive materials. Here, the study reports highly stretchable, nonhygroscopic, and biocompatible SDAs developed through the synergistic effects of tannic acid and polyol compounds.
View Article and Find Full Text PDFFront Plant Sci
August 2022
Division of Cellular Dynamics, National Institute for Basic Biology, Okazaki, Aichi, Japan.
Eukaryotic cells possess endomembrane organelles equipped with specific sets of proteins, lipids, and polysaccharides that are fundamental for realizing each organelle's specific function and shape. A tightly regulated membrane trafficking system mediates the transportation and localization of these substances. Generally, the secretory/exocytic pathway is responsible for transporting cargo to the plasma membrane and/or the extracellular space.
View Article and Find Full Text PDFFront Plant Sci
April 2022
Department of Biology, Swarthmore College, Swarthmore, PA, United States.
Phospholipid biosynthesis is a core metabolic pathway that affects all aspects of plant growth and development. One of the earliest step in this pathway is mediated by choline/ethanolamine kinases (CEKs), enzymes in the Kennedy pathway that catalyze the synthesis of the polar head groups found on the most abundant plant phospholipids. The Arabidopsis genome encodes four s.
View Article and Find Full Text PDFBiomedicines
December 2021
Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Glioblastoma multiforme (GBM), a grade IV astrocytoma, is a lethal brain tumor with a poor prognosis. Despite recent advances in the molecular biology of GBM, neuro-oncologists have very limited treatment options available to improve the survival of GBM patients. A prominent signaling pathway implicated in GBM pathogenesis is that of the mechanistic target of rapamycin (mTOR).
View Article and Find Full Text PDFBioinspir Biomim
August 2021
Department of Mechanical and Aerospace Engineering, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093, United States of America.