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Background: The purpose of case report was to present a rare case of a solitary metastasis of myxoid liposarcoma and discuss the clinical and pathological information for patients treated for metastatic myxoid liposarcoma.
Case Presentation: We report our experience with a case of solitary metastasis of myxoid liposarcoma from the thigh to intraperitoneum. The patient was a 60-year-old man who was referred for abdominal discomfort and fatigue. Enhanced computed tomography showed a 25-cm intra-abdominal tumor. He had undergone a wide local excision for a right thigh myxoid liposarcoma 6 years earlier. At laparotomy, a huge multi-lobular cystic mass was identified at the small bowel mesentery. Wide local excision was performed, and the mass was diagnosed as metastatic myxoid liposarcoma. He was discharged without postoperative complications.
Conclusions: We experienced a single intraperitoneal metastasis in a patient with myxoid liposarcoma after radical surgery of the primary site.
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http://dx.doi.org/10.1186/s12957-019-1724-3 | DOI Listing |
Am J Surg Pathol
September 2025
Department of Pathology.
Perinephric myxoid pseudotumor of fat (PMPTF) is a recently characterized lesion typically associated with non-neoplastic renal disease. Its pathogenesis is thought to result from chronic renal "irritation," either due to mass effect from renal carcinoma or inflammation related to benign renal conditions. Prompted by several cases arising in the absence of underlying renal pathology, we conducted a multi-institutional study of 29 mass-forming cases with detailed clinical, histologic, and molecular characterization.
View Article and Find Full Text PDFRadiol Case Rep
November 2025
Department of Radiology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor, Malaysia.
Liposarcoma is a rare soft-tissue sarcoma accounting for about 5% of adult cases; myxoid liposarcoma is the second most common subtype and typically arises in the lower extremities (especially the thigh). We report the case of a 48-year-old woman who presented with a rapidly enlarging, painful mass in the left thigh over 1 year, which was confirmed to be a myxoid liposarcoma on histopathological examination. The patient underwent wide local excision of the tumor with clear margins; she had an uncomplicated postoperative course and remained disease-free at 6 months of follow-up.
View Article and Find Full Text PDFBMJ Case Rep
August 2025
Department of Surgery, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.
We present a case of successful resection of a fourth recurrence of oligometastatic myxoid liposarcoma to the retroperitoneum. This case highlights the importance of centralised sarcoma centres with high surgical and patient volume, extensive perioperative work-up and the multidisciplinary management of patients with sarcoma. Perioperative work-up included a CT coronary angiogram, which identified intraventricular cardiac metastasis.
View Article and Find Full Text PDFReports (MDPI)
July 2025
Department of Orthopedics and Traumatology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Myxoid liposarcoma (MLS) is a malignant soft tissue tumor that often presents as a painless, slow-growing mass and is known for its atypical extrapulmonary metastatic pattern. Although sciatic nerve involvement is rare, when present, it usually causes neurologic symptoms. In this case, a large MLS silently expanded and completely encased the sciatic nerve without causing deficits, highlighting the importance of early imaging, multidisciplinary planning, and individualized surgical strategy in managing complex soft tissue sarcomas.
View Article and Find Full Text PDFCancer Res Commun
August 2025
Nationwide Children's Hospital, Columbus, OH, United States.
Genes encoding the RNA-binding proteins FUS, EWSR1, and TAF15 (FET proteins) are involved in chromosomal translocations in rare sarcomas. The encoded fusion oncoproteins typically include a DNA binding domain and function as oncogenic transcription factors. FET-rearranged sarcomas are often aggressive malignancies affecting patients of all ages.
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