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While research suggests that the therapeutic alliance is important in predicting outcomes of psychotherapy, relatively little is known about the development of the alliance or the moment-to-moment components of the relationship and how they combine to create an alliance, which may represent a serious limitation in existing methods of measurement. Language style matching (LSM), or the degree to which unconscious aspects of an interactional partner's language mimic that of the other partner, is a promising, unobtrusive measure of interaction quality that could provide novel insight into the therapist-client alliance. In this article, we present a theoretical argument regarding the trajectory of therapist-client LSM across therapy sessions, as well as potential precursors and consequences of LSM. We then report on a pilot test of our hypotheses that examined how LSM, clients' relational histories, and clients' symptoms were associated within a therapeutic context. Using a small sample of substance dependent mothers ( = 7, 100% Caucasian women) enrolled in a randomized controlled trial of psychodynamic psychotherapy lasting 12 sessions, we examined client and therapist LSM across 4 of the 12 sessions. We found that, on average, LSM decreases over the course of treatment. Furthermore, greater client interpersonal problems prospectively predict lower early LSM in therapist-client dyads, which in turn predicts greater posttreatment psychiatric distress. Results generate questions for future research and support further investigations of LSM as one index of the quality of interactions between therapist and client.
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http://dx.doi.org/10.1037/pap0000177 | DOI Listing |
Geroscience
September 2025
Faculty of Social Welfare & Health Sciences, The Cheryl Spencer Department of Nursing, University of Haifa, Haifa, Israel.
Life space mobility (LSM) is important for participation in daily life. It is influenced by individual and environmental factors and tends to decline with age. Although LSM has been studied in older adults, stratification of this population into age subgroups has not been performed, creating a gap in understanding the factors associated with LSM in a more granular manner.
View Article and Find Full Text PDFJ Neurosci
September 2025
Northwestern University, Feinberg School of Medicine, Department of Cell and Developmental Biology Chicago, IL 60611-3008
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by mislocalization and aggregation of proteins in motor neurons. Ataxin-2 (ATXN2), an RNA-binding protein harboring 22-polyglutamine (polyQ) repeats, is a risk factor for ALS, when its polyQ repeats are expanded to 27-33 repeats. However, the physiological function of ATXN2 beyond its role in RNA regulation, and how polyQ expansion in ATXN2 increases risk for ALS, remain unclear.
View Article and Find Full Text PDFNeuroimage Clin
August 2025
Department of Psychology, University of South Carolina, Columbia, SC, USA.
Introduction: Stroke can lead to neurological changes beyond the initial lesion site, including post-stroke crossed-cerebellar degeneration. While traditional methods typically rely on total lesion volume to assess remote effects, the spatial distribution of lesions may more accurately predict cerebellar atrophy and associated functional deficits. This study investigated whether anatomically specific cortical lesions contribute to cerebellar gray matter volume loss, expanding on the hypothesis that cerebellar atrophy may reflect more than global brain injury severity, and instead result from targeted disruption of cortico-cerebellar pathways.
View Article and Find Full Text PDFWorld J Gastroenterol
August 2025
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, United States.
Background: Cardiopulmonary changes in noncirrhotic portal hypertension (NCPH) are poorly understood.
Aim: To investigate cardiopulmonary changes using transthoracic echocardiography (TTE) in NCPH and their correlation with clinical features.
Methods: Prospective cohort including 10 preclinical NCPH [without portal hypertension (PH)] and 32 NCPH subjects who underwent TTE with agitated saline injection and comprehensive clinical evaluation were assessed.
Neurotherapeutics
September 2025
Clintrex, 2 North Tamiami Trail, Suite 308 Sarasota, Florida 34236, USA.
Despite current medical therapy for Parkinson's Disease (PD), many experience persistent motor symptoms and significant unmanaged non-motor issues. Previous studies suggest that light therapy (LT) provides benefits for motor and non-motor features of PD. This study evaluated Circadian Effective LT (CELT) with a spectral band between 460 and 545 nm for the motor and non-motor features of PD.
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