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Article Abstract

The highly oxygenated pimarane diterpenoids basimarols A, B, and C (-) were isolated from the plant species , which was collected within the Australian arid zone. Structure elucidation was performed using a suite of spectroscopic techniques, including X-ray crystallography. Anticancer and anti-DENV activity of - was explored, but only limited activity was observed. More extensive antiviral evaluation of stachyonic acid A (), which was also isolated from , revealed broad spectrum antiviral activity against West Nile virus (Kunjin strain, WNV) and human influenza viruses H1N1 and H3N2.

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http://dx.doi.org/10.1021/acs.jnatprod.9b00522DOI Listing

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