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http://dx.doi.org/10.1007/s00467-019-04348-x | DOI Listing |
Kidney360
August 2025
Dept of Paediatrics, Lady Hardinge Medical College and assoc. Kalawati Saran Children's Hospital, New Delhi, India.
Background: Urine sediment examination is an important preliminary investigation for the nephrologist and helps him decide whether the patient has a proliferative or non-proliferative glomerular pathology. Recently, there is an increasing trend of using easier, non-specific dipstick method for urine examination leading to a decline in the importance of urine sediment examination. Here, we attempt to define guidelines for bio-chemical and microscopic parameters in order to develop a uniform and clinically relevant reporting system for urine sediment examination.
View Article and Find Full Text PDFKidney Med
September 2025
Division of Nephrology, University of California Davis School of Medicine, Sacramento, CA.
Individuals of recent African ancestry are disproportionately affected by kidney disease. The discovery of the Apolipoprotein L1 ( gene and, subsequently, the G1 and G2 risk alleles has helped to understand some of these disparities. The gene does not appear to be necessary for normal kidney function, and the high-risk alleles appear to be gain of function mutations offering protection against species.
View Article and Find Full Text PDFKidney360
August 2025
School of Medicine, University College Dublin, Dublin, Ireland.
Background: Differentiating functional acute kidney injury (AKI) from structural/intrinsic AKI with tubular injury remains a clinical challenge. Urinary NGAL (uNGAL) has shown promise in distinguishing these conditions. This study evaluated the implementation of uNGAL in a heterogeneous medical cohort at an academic tertiary care center in Ireland over a three-year period.
View Article and Find Full Text PDFNephrol Dial Transplant
July 2025
Division of Nephrology, Cliniques universitaires Saint-Luc, UCLouvain, Brussels, Belgium.
Hemodialysis removes uremic toxins and excess water and sodium from the blood of patients with kidney failure. For the last 60 years, this technique has been extensively improved in order to optimize patient survival and mimimize adverse events. Indeed, life-threatening complications related to hemodialysis have become very rare with the use of modern machines and equipment.
View Article and Find Full Text PDFClin Exp Nephrol
June 2025
Department of Nephrology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Background: Whole slide imaging (WSI) is digital imaging technique that involves scanning glass slides. Although WSI is widely used in pathological diagnosis and education, its impact on nephrology education remains unknown. We clarified the usefulness of WSI in rapid treatment decision-making and education in renal pathology.
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