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The incidence of skin tumors has steadily increased. Although most are benign and do not affect survival, some of the more malignant skin tumors present a lethal threat if a delay in diagnosis permits them to become advanced. Ideally, an inspection by an expert dermatologist would accurately detect malignant skin tumors in the early stage; however, it is not practical for every single patient to receive intensive screening by dermatologists. To overcome this issue, many studies are ongoing to develop dermatologist-level, computer-aided diagnostics. Whereas, many systems that can classify dermoscopic images at this dermatologist-equivalent level have been reported, a much fewer number of systems that can classify conventional clinical images have been reported thus far. Recently, the introduction of deep-learning technology, a method that automatically extracts a set of representative features for further classification has dramatically improved classification efficacy. This new technology has the potential to improve the computer classification accuracy of conventional clinical images to the level of skilled dermatologists. In this review, this new technology and present development of computer-aided skin tumor classifiers will be summarized.
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http://dx.doi.org/10.3389/fmed.2019.00191 | DOI Listing |
JMIR Dermatol
September 2025
College of Osteopathic Medicine, Rocky Vista University, 8401 S Chambers Road, Parker, CO, 80112, United States, 1 9253236431.
Dermal fillers have gained increasing popularity for their ability to enhance facial symmetry, restore volume, and improve skin texture. However, their use in patients with cancer undergoing active chemotherapy and radiation therapy poses unique challenges, as these treatments can alter both the safety profile and efficacy of filler procedures. Chemotherapy can interfere with normal wound healing and immune responses, warranting a more cautious and individualized approach when considering dermal fillers in this population.
View Article and Find Full Text PDFAerosp Med Hum Perform
September 2025
Introduction: Pilots have an increased incidence of cutaneous melanoma compared to the general population; occupational exposure to ultraviolet (UV) radiation is one of several potential risk factors. Cockpit windshields effectively block UVB (280-315 nm) but further analysis is needed for UVA (315-400 nm). The objective of this observational study was to assess transmission of UVA through cockpit windshields and to measure doses of UVA at pilots' skin under daytime flying conditions.
View Article and Find Full Text PDFPLoS One
September 2025
Department Chemicals and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.
Tattoos and permanent make-up (PMU) gain increasing popularity among the general population. There are indications that pigments or their fragments may translocate within the body, however knowledge about possible systemic adverse effects related to tattoos is very limited. We investigated the prevalence of systemic chronic health effects including cardiovascular diseases, cancer and liver toxicity and their relationship with the presence and characteristics of tattoos and PMU as part of the LIFE-Adult-study, a population-based cohort study.
View Article and Find Full Text PDFAm J Case Rep
September 2025
Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei, Taiwan.
BACKGROUND This study reports on 2 cases of cervical melanoma with similar presentations but at different stages, and the treatment strategy varied accordingly, and we review the literature on the characteristics, diagnosis, and management of cervical melanoma. CASE REPORT Case 1: A 69-year-old woman with abnormal vaginal bleeding was diagnosed with advanced cervical melanoma, staged as International Federation of Gynecology and Obstetrics (FIGO) Stage IVB, involving multiple metastases. Despite chemoradiotherapy and immunotherapy (nivolumab), the disease progressed rapidly, and the patient died 4 months after diagnosis.
View Article and Find Full Text PDFJ Korean Med Sci
September 2025
Department of Transdisciplinary Medicine, Seoul National University Hospital, Seoul, Korea.
Background: With the increasing incidence of skin cancer, the workload for pathologists has surged. The diagnosis of skin samples, especially for complex lesions such as malignant melanomas and melanocytic lesions, has shown higher diagnostic variability compared to other organ samples. Consequently, artificial intelligence (AI)-based diagnostic assistance programs are increasingly needed to support dermatopathologists in achieving more consistent diagnoses.
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