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Article Abstract
The catalytic asymmetric synthesis of α,α-difluoromethylated tertiary alcohols is described, using an asymmetric dihydroxylation reaction. This protocol using either the AD-mix-α or AD-mix-β allowed an easy access to these valuable fluorinated chiral building blocks, which have been obtained with excellent yields and er. In addition, the reaction was extended to the α-fluoromethylated analogues.
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