Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1126/science.aay7101 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Wnt signaling - using the bloodstream to send a message.
Cell Mol Life Sci
August 2025
Department of Clinical Microbiology and Immunology, Grey Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Wnt signaling is one of the cell's most complex and important signal transduction pathways. This pathway, which is divided into additional sub-pathways, regulates cell growth, motility, polarity, and differentiation during embryonic development as well as stem cell regeneration. In addition, the Wnt cascades are involved in maintaining different aspects of adult homeostasis.
View Article and Find Full Text PDFFlexible and scalable participatory syndromic and virological surveillance for respiratory infections: Our experiences in The Netherlands.
PLoS One
August 2025
Dutch National Institute for Public Health and the Environment (RIVM), Centre for Infectious Disease Control (CIb), Bilthoven, The Netherlands.
Background: During the COVID-19 pandemic participatory digital surveillance of symptoms (syndromic surveillance) re-established itself as a worthy addition to the surveillance pyramid, as they are scalable, flexible and function independent from the health care system or health care seeking behaviour. A limitation of syndromic surveillance however is the inability of pathogen identification. We describe our experiences regarding integrating self-swabs with centralized testing into a participatory syndromic surveillance system in the Netherlands (Infectieradar).
View Article and Find Full Text PDFGenome-wide association study of borderline personality disorder identifies 11 loci and highlights shared risk with mental and somatic disorders.
medRxiv
August 2025
Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
We conducted the largest genome-wide meta-analysis of borderline personality disorder (BPD) to date, with a discovery sample of 12,339 cases and 1,041,717 controls, and a replication study of 685 cases and 107,750 controls (all participants of European ancestry). We identified 11 independent associated genomic loci, and nine risk genes in the gene-based analysis. We observed a single-nucleotide polymorphism (SNP) heritability of 17.
View Article and Find Full Text PDFEvaluation of the user experience for a point of care molecular test for causes of vaginitis.
BMC Infect Dis
August 2025
Cepheid Inc, Sunnyvale, CA, US.
Background: Vaginitis is a major cause of healthcare visits in the US, costing over $1.2 billion annually. Point-of-care (POC) nucleic acid amplification tests (NAATs) could improve accuracy of diagnosis and treatment during initial visit for vaginitis compared to send-out NAATs.
View Article and Find Full Text PDFPeritonsillar abscess in children: A retrospective analysis on surgical and antimicrobial approaches.
PLoS One
July 2025
Department of Otorhinolaryngology, University Medical Center Bonn, Bonn, Germany.
Background: Peritonsillar abscess (PTA) is a prevalent infection for specialists in otorhinolaryngology and pediatric primary care providers, that has the potential to cause severe complications. The aim of this study is to investigate the surgical treatment of pediatric peritonsillar abscesses and to compare the risk profiles of bilateral surgery versus surgery on the affected side alone. In addition, the evaluation of the microbiological smears obtained intraoperatively should provide information on whether the calculated antibiotic therapy adequately covers the microbial spectrum.
View Article and Find Full Text PDF