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http://dx.doi.org/10.1002/lary.28230 | DOI Listing |
Laryngoscope
February 2023
Rehabilitation Medicine, NYU Grossman School of Medicine, New York, U.S.A.
Objectives: Functional outcomes following microflap surgery for vocal fold pathology are favorable. Although the stratified squamous epithelium appears to heal rapidly, persistent physiologic tissue alterations are likely. We sought to elucidate key biochemical processes including recruitment of immune cells, regulation of cellular junction proteins, and long-term alterations to epithelial tissue permeability following microflap with an eye toward enhanced clinical outcomes.
View Article and Find Full Text PDFJ Voice
January 2024
Istanbul Training and Research Hospital, Pathology Department, University of Health Sciences, Istanbul, Turkey.
Objective: Mesna triggers chemical dissection in tissues by breaking down disulfide bonds and is used during surgical dissections in several areas. In this study, we aimed to investigate the effect of submucosal mesna infiltration on microflap elevation and the histopathological findings of its effects on the vocal fold lamina propria in a rabbit model.
Methods: Eight adult male New Zealand white rabbits were used in the study.
Laryngoscope
September 2021
Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Soonchunhyang University, Cheonan, South Korea.
Objectives/hypothesis: Microsurgical removal with a microflap technique via direct laryngoscopy is considered the primary treatment option for vocal cysts. However, the microflap technique is technically difficult and challenging. Therefore, we developed the "cotton ball self-retraction" technique to aid in vocal cyst surgery and reduce the cyst rupture incidence.
View Article and Find Full Text PDFLaryngoscope
May 2020
Department of Otorhinolaryngology, Myunggok Medical Research Institute, Konyang University Hospital, Konyang University College of Medicine, Daejeon, South Korea.
Ann Otol Rhinol Laryngol
April 2019
1 Clinic of Otolaryngology, Head and Neck Surgery, Department of Translational Surgery and Medicine, Careggi University Hospital, Florence, Italy.
Objectives:: The aim of this study was to assess the feasibility of the submucosal infusion combined with microflap dissection via laser CO2 as both a diagnostic and therapeutic procedure for superficial glottic lesions. To define a safe surgical procedure in terms of local control, a morphometric study of surgical margins was performed.
Methods:: From January 2011 to January 2016, we treated 122 patients with early glottic lesions with phonomicrosurgery.