Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

This is the case of a 27-year-old male patient with a newly diagnosed extensive lymphomatoid papulosis type A involving cosmetically sensitive areas (e.g. face), who refused to be treated with a low dose of methotrexate, as recommended by the published literature. The natural course of the disease was proved to be strikingly satisfying though, with a complete regression of all skin lesions at the 4-week follow-up, including an ulcerated nodule 3 x 3 cm in dimension, which was expected to heal at least in months. We report this case to reconsider weighting the risks and the short-term benefits of methotrexate treatment, even in the case of an extensive disease.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662440PMC
http://dx.doi.org/10.1155/2019/1765210DOI Listing

Publication Analysis

Top Keywords

lymphomatoid papulosis
8
papulosis type
8
27-year-old male
8
male patient
8
extensive disease
8
case
4
type case
4
case report
4
report "wait-and-see
4
"wait-and-see strategy"
4

Similar Publications

Lymphomatoid papulosis (LyP) is a rare cutaneous lymphoproliferative disorder involving the dysregulation of CD30-positive T-cells that accumulate in the skin. The accumulation of CD30-positive T-cells leads to the development of papulonodular lesions, which typically follow a protracted course and often resolve spontaneously in a matter of days to weeks. This case report describes a 44-year-old male patient who initially presented to the dermatology office with recurrent nodules under the right eye.

View Article and Find Full Text PDF

: Lymphomatoid papulosis (LyP) is a primary cutaneous CD30-positive T-cell lymphoproliferative disorder presenting with self-healing erythematous papulonodular lesions that may ulcerate and scar. Treatment varies by lesion extent, location, and severity. : We describe a 57-year-old man with acral LyP successfully treated with chlormethine gel (CG).

View Article and Find Full Text PDF

Background: Lymphomatoid papulosis (LyP) is a rare, chronic, recurrent, self-healing, indolent cutaneous lymphoproliferative disorder. Histologically, it resembles malignant lymphoma; however, its clinical manifestations are predominantly characterized by benign behaviors, including recurrent papules, nodules, and necrotic lesions.

Case Presentation: We report a case of a middle-aged female who initially presented with a giant ulcer on the right foot and was surgically treated at another hospital as a keratoacanthoma (KA).

View Article and Find Full Text PDF