Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Purpose: The purpose of this study was to determine whether the adjunctive use of plasma rich in growth factors in postextraction sites could be beneficial in terms of hard- and soft-tissue healing and patients' comfort.
Materials And Methods: An electronic search was performed on MEDLINE, EMBASE, Scopus, and CENTRAL. Only controlled clinical trials or randomized clinical trials that used plasma rich in growth factors in the test group were included. The primary outcomes were pain assessment, complications, and adverse events. Secondary outcomes were hard-tissue healing, bone remodeling, and soft-tissue healing.
Results: Eight comparative studies (5 randomized clinical trials) were included. Four studies had a split-mouth design. Six hundred fourteen teeth were extracted in 338 patients. Only qualitative analysis could be performed. Postoperative pain and the incidence of complications such as alveolar osteitis were consistently lower in the test group. Hard-tissue healing, evaluated by clinical, radiographic, histologic, and histomorphometric techniques, showed significantly better results for the test group in almost all studies. Better epithelialization, keratinized tissue thickness, and healing score were also reported.
Conclusion: Plasma rich in growth factors may bring advantages in some relevant clinical and radiographic outcomes, such as bone density and soft-tissue healing, after tooth extraction. It could also represent a useful tool for reducing adverse events, complications, and patients' discomfort, although it is still not quantifiable.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jebdp.2018.11.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Calcified vs. Non-Calcified Tendinopathy of the Rotator Cuff: Clinical Presentations, Prognostic Implications, and Emerging Therapeutic Strategies.
J Orthop Sports Med
August 2025
Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California, 91766, USA.
Rotator cuff tendinopathy is a common cause of shoulder pain and dysfunction, presenting in two primary forms: calcific and non-calcific. These subtypes differ significantly in their pathophysiology, clinical manifestations, and natural history, necessitating tailored diagnostic and therapeutic approaches. This review delineates the clinical presentations of calcific rotator cuff tendinopathy (RCCT), characterized by distinct pre-calcific, calcific, and post-calcific stages, and contrasts them with the more insidious, degenerative course of non-calcific rotator cuff tendinopathy.
View Article and Find Full Text PDFBackground: Rotator cuff injuries are very common in the athletic population and both corticosteroid injections and platelets enriched plasma (PRP) are common management options used in clinical practice yet there aren't any recent systematic reviews that compare between the two, thus, this study aims to provide a high-quality systematic review of the clinical trials and the experimentation found in the literature as of yet to guide practitioners in choosing between these two management options.
Methods: This systematic review was conducted in accordance to PRISMA guidelines and was registered in PROSPERO (CRD4202461663). A comprehensive search was done in the following databases MEDLINE, Web of Science, Google Scholar.
Select bioavailable metabolites from and extracts exhibit anticancer effects on pancreatic cancer cell lines.
Food Funct
September 2025
Department of Nutrition, University of California, Davis, Davis, 95616 CA, USA.
Phenolic compounds are widely recognized for their anti-proliferative and chemopreventive properties, making them potential candidates for cancer therapy. (LC) and (OE) are two phenolic-rich plant extracts with established antitumor activity. Despite their distinct phytochemical compositions, a clinical intervention study identified nine common bioavailable metabolites in human plasma following ingestion of these extracts.
View Article and Find Full Text PDFManaging Erectile Dysfunction After Pelvic Radiotherapy.
Rev Recent Clin Trials
September 2025
Department of Radiation Oncology, University Hospital of Iraklion, 71110, Iraklion, Greece.
Introduction: Radiotherapy (RT) is an integral component of various multidisciplinary treatment approaches for pelvic malignancies, used both in the radical and adjuvant setting. Despite the improvement of radiotherapy modalities, pelvic radiotherapy often induces permanent erectile dysfunction (ED). However, post-treatment ED receives little medical attention, since patient follow-up focuses mainly on cancer recurrence surveillance.
View Article and Find Full Text PDFIngestion of a lipid-rich meat matrix blunts the post-exercise increase of myofibrillar protein synthesis rates in healthy adults: A randomized controlled trial.
Am J Clin Nutr
September 2025
Department of Health and Kinesiology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA; Division of Nutritional Sciences, University of Illinois Urbana-Champaign, Urbana, Illinois, USA. Electronic address:
Background: There is considerable variation in the anabolic action of ingesting protein-dense foods on the stimulation of postprandial myofibrillar protein synthesis rates (MPS) despite ingesting similar amounts of protein and essential amino acids (EAA) OBJECTIVES: To determine the effects of consuming high-fat pork (HFP), low-fat pork (LFP), or a carbohydrate control (CHO) on the MPS response METHODS: In a semi-crossover design, sixteen physically active adults (25 ± 5 y; 25.0 ± 2.3 kg·m; 12M, 4F) received primed-constant infusions of L-[ring-C]phenylalanine and performed an acute bout of resistance exercise.
View Article and Find Full Text PDF