Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objective: The objective of this study was to evaluate the utility of frozen section (FS) in detecting occult nodal metastasis in cN0 OSCC and its impact on regional failure and survival.
Materials And Methods: Clinical records of patients of OSCC operated from January 2013 to December 2014 were retrospectively reviewed. These patients were divided into two groups-Group A comprised of patients who underwent selective neck dissection (SND) (level III/IV) and FS based completion (level IV ± V); Group B included patients who underwent SND I-III/IV without FS. The sensitivity and specificity of FS in detecting occult metastasis was calculated. The regional failure rates and overall survival (OS) between the two groups were compared.
Results: The sensitivity, specificity, PPV (positive predictive value) and NPV (negative predictive value) of FS in detecting occult metastasis were 64.06%, 100%, 100%, and 92.15%, respectively. There was no significant difference in regional failure rates (p = 0.219) and OS (p = 0.08) between the two groups.
Conclusion: FS has a poor sensitivity in detecting occult nodal metastasis. FS-guided neck dissection does not have a significant impact in reducing regional failure or improving OS in clinically node-negative neck in oral cavity carcinomas.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00405-019-05484-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Methods for the analysis of leukemic infiltration within cerebrospinal fluid in acute lymphoblastic leukemia-a systematic review.
Leuk Lymphoma
September 2025
Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Central nervous system (CNS) involvement in acute lymphoblastic leukemia (ALL) is associated with a poor prognosis, making its accurate detection vital for treatment planning. This systematic review critically examines the role of conventional cytomorphology (CC) and multiparameter flow cytometry (FC) in analyzing cerebrospinal fluid in acute lymphoblastic leukemia cases. While CC remains the gold standard, its sensitivity is limited, particularly in cases with low cell counts.
View Article and Find Full Text PDFModeled Cost-Effectiveness of a Rideshare Program to Facilitate Colonoscopy Completion.
JAMA Netw Open
September 2025
Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, Washington.
Importance: In colorectal cancer (CRC) screening, too many patients fail to receive follow-up colonoscopy after an abnormal fecal immunochemical test (FIT), and transportation is a frequently reported barrier.
Objective: To determine the outcomes and cost-effectiveness of providing a rideshare intervention to patients with abnormal FIT results.
Design, Setting, And Participants: The CRC-Simulated Population Model for Incidence and Natural History microsimulation model was used to simulate the outcomes and cost-effectiveness of a rideshare intervention to improve colonoscopy completion in a population-based CRC screening program.
Challenges in diagnosis of sarcoidosis.
Curr Opin Immunol
September 2025
Center for Interstitial and Rare Lung Diseases, Pneumology Department, University Hospital Essen, Ruhrlandklinik, Essen, Germany.
Purpose Of Review: Diagnosing sarcoidosis remains challenging. Histology findings and a variable clinical presentation can mimic other infectious, malignant, and autoimmune diseases. This review synthesizes current evidence on histopathology, sampling techniques, imaging modalities, and biomarkers and explores how emerging 'omics' and artificial intelligence tools may sharpen diagnostic accuracy.
View Article and Find Full Text PDFMultisystem fatal metastasis of large cell lung carcinoma (LCLC) masquerading as acute cerebral infarction: A case report.
Medicine (Baltimore)
August 2025
Key Laboratory of Evidence Science, China University of Political Science and Law, Ministry of Education, Beijing, China.
Rationale: Large cell lung carcinoma (LCLC) is a rare undifferentiated malignant epithelial tumor of the lung. The diagnostic complexity of LCLC stems from its pronounced histological heterogeneity and diverse clinical presentation, particularly when extrapulmonary manifestations constitute the initial disease presentation, complicating early detection.
Patient Concerns: A 58-year-old smoker presented with acute-onset dizziness, lethargy, and communication difficulties lasting 1 day.
Diagnostic Accuracy of the Faecal Immunochemical Test in Triage of Symptomatic Patients Referred for Colonoscopy: A Prospective Single-Centre Study.
Can J Gastroenterol Hepatol
September 2025
Department of Gastroenterology, St Luke's General Hospital, Kilkenny, Ireland.
The faecal immunochemical test (FIT) is endorsed by NICE for triaging symptomatic patients referred from primary care. This prospective diagnostic accuracy study assessed the performance of FIT in detecting significant colorectal pathology among symptomatic patients referred for colonoscopy in secondary care. Between May 2023 and May 2024, FIT kits were distributed to 1296 adult patients referred for lower gastrointestinal (GI) endoscopy.
View Article and Find Full Text PDF