Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Purpose: To evaluate the relationship between retinal traction caused by epiretinal membrane and visual functions.
Methods: In this institutional study, en face swept-source optical coherence tomography images of 141 eyes of 130 patients with epiretinal membrane were analyzed to investigate maximum depth of retinal folds, which represents retinal traction strength and the distribution pattern of retinal folds. We investigated the relationships between the maximum depth and distribution pattern of retinal folds and visual functions as well as the effects of membrane peeling.
Results: Maximum retinal fold depth was significantly correlated with the metamorphopsia score (P < 0.001). Fifteen eyes showed retinal folds radially extending from the macular epiretinal membrane (radiating folds group), whereas 126 eyes showed a multidirectional pattern of retinal folds (multidirectional folds group). The radiating folds group showed a significantly lower metamorphopsia score (P = 0.014). Multiple regression analysis revealed that the metamorphopsia score was significantly related to maximum retinal fold depth (P = 0.003), distribution pattern (P = 0.015), and central retinal thickness (P < 0.001). One month after membrane peeling, parafoveal retinal folds resolved completely in all cases, and both visual acuity (P < 0.001) and average metamorphopsia score (P = 0.036) were significantly improved.
Conclusion: Both the strength and the distribution pattern of retinal traction are significantly related to metamorphopsia in epiretinal membrane patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/IAE.0000000000002569 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A Case of CHARGE Syndrome with a Novel Intronic Variant in the Gene.
J Clin Res Pediatr Endocrinol
September 2025
İnönü University Faculty of Medicine, Department of Medical Genetics, Malatya, Türkiye.
CHARGE syndrome is an autosomal dominant disorder caused by variations in the CHD7 gene. The characteristic findings of the syndrome include coloboma (C), heart anomalies (H), choanal atresia (A), growth and developmental delay (R), genitourinary system anomalies (G), and ear anomalies and/or hearing loss (E). A 7.
View Article and Find Full Text PDFPotential role of endoplasmic reticulum quality control in retinal degenerative diseases.
Neuroscience
August 2025
Department of Ophthalmology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China. Electronic address:
The endoplasmic reticulum (ER) is the largest organelle in eukaryotic cells, and it plays a crucial role in regulating various biological processes, including protein folding, translation, and structural maturation. Accurate protein modification is essential for maintaining oxidative stress, apoptosis, and cellular senescence in the organism. The regulation of protein homeostasis involves three biological processes: endoplasmic reticulum stress (ERS), endoplasmic reticulum autophagy (ERPA), and endoplasmic reticulum-associated degradation (ERAD).
View Article and Find Full Text PDFOptic Nerve Atrophy Conditions Associated With 3D Unsegmented Optical Coherence Tomography Volumes Using Deep Learning.
JAMA Ophthalmol
August 2025
Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York.
Importance: Accurate differentiation of optic nerve head (ONH) atrophy is vital for guiding diagnosis and treatment of conditions such as glaucoma, nonarteritic anterior ischemic optic neuropathy (NAION), and optic neuritis. Traditional 2-dimensional assessments may overlook subtle, volumetric changes.
Objective: To determine whether a 3-dimensional (3D) deep learning model trained on unsegmented ONH optical coherence tomography (OCT) scans can reliably distinguish optic atrophy in glaucoma, NAION, optic neuritis, and healthy eyes.
Approach to optic disc swelling with macular subretinal fluid and choroidal folds: a narrative review.
Photodiagnosis Photodyn Ther
August 2025
Department of Ophthalmology, Tung Wah Eastern Hospital, Hong Kong. Electronic address:
Influence of drainage retinotomy on anatomical and visual outcomes of pars plana vitrectomy for primary rhegmatogenous retinal detachment.
BMJ Open Ophthalmol
August 2025
University of Newcastle upon Tyne, Newcastle upon Tyne, Tyne and Wear, UK.
Objectives: To assess the influence of drainage retinotomy (DrR) on anatomical and visual outcomes of pars plana vitrectomy (PPV) for primary uncomplicated rhegmatogenous retinal detachment (RD), compared with drainage through pre-existing retinal break (PRB).
Methods And Analysis: Retrospective study on patients treated with PPV for RD. Prospectively collected data were extracted from the Britain & Eire Association of Vitreoretinal Surgeons and European Society of Retina Specialists (EURETINA) RD database, including baseline features, surgical details, and anatomical and functional outcomes.