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The temperature-humidity index (THI) has been extensively applied for assessing heat stress in moderate to hot conditions in dairy cattle. However, there exist wide variation between researchers in defining an appropriate range of THI values for denoting different levels of stress. The present study was aimed to reassess previously described heat stress indicators of dairy cattle of sub-tropical region of India. From comparative evaluation of meteorological data over previous four years (2014-2017) the period of year when high THI prevailed in the region was determined. Accordingly, the time period of sample collection and observation on animals was decided, so that a THI range of 68-86 could be covered. After analyzing physiological, biochemical parameters and expression profile of heat shock response (HSR) genes of animals in response to different THI, it was evident from the study that animal undergoes few or little changes at THI 72, but major physiological changes occurred after THI reached 74. At THI range 74-79, no drastic change in these parameters occurred suggesting animals undergo transient acclimatization in this range to maintain homeostasis. Once THI reached and crossed 80, this homeostasis was perturbed and animals experienced major physiological changes again. Overall, the study suggests that THI values indicating level of heat stress are dependent on the geographic location, as well as type of animal and therefore, existing THI should be recalibrated for different climatic region for accurate assessment of the heat stress.
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http://dx.doi.org/10.1016/j.jtherbio.2019.03.017 | DOI Listing |
Proc Natl Acad Sci U S A
September 2025
Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba 305-8577, Japan.
All organisms are exposed to various stressors, which can sometimes lead to organismal death, depending on their intensity. While stress-induced organismal death has been observed in many species, the underlying mechanisms remain unclear. In this study, we investigated the molecular mechanisms of stress-induced organismal death in the fruit fly .
View Article and Find Full Text PDFVet Res Commun
September 2025
Department of Animal Industry Convergence, Kangwon National University, Chuncheon, 24341, Republic of Korea.
Global warming causes heat stress in livestock, impairing their health, welfare, and productivity. In bovines, chronic stress elevates cortisol levels; however, this response often goes undetected due to the lack of practical biomatrices for accurate assessment. Common biomatrices such as blood require repeated sampling that may affect measurement accuracy.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
Chemical and Biological Engineering, University of Ottawa, 161 Louis Pasteur, Ottawa, Ontario K1N 6N5, Canada.
The processes of thermoforming 2D-printed electronics into 3D structures can introduce defects that impact the electrical performance of conductors, making them more susceptible to thermal failure during high electrical power/current applications on temperature-sensitive substrates. We therefore report the use of a thin-film boron nitride nanotube (BNNT) interlayer to directly reduce heat stress on linear and serpentine metallic traces on polycarbonate substrates thermoformed to 3D spherocylindrical geometries at varying elongation percentages. We demonstrate that the BNNT interlayer helps to improve the electrical conductivity of highly elongated thermoformed 3D traces in comparison to traces on bare polycarbonate.
View Article and Find Full Text PDFInt J Soc Psychiatry
September 2025
Department of Psychiatry, King George's Medical University, Lucknow, Uttar Pradesh, India.
Background: Climate distress is a psychological reaction to adverse weather events and climate change. These events can increase people's vulnerability to develop psychiatric disorders like anxiety, depression, and PTSD particularly in disaster-prone regions like India.
Aim: To explore the relationship between climate distress and psychological impact with a particular emphasis on women, elderly, and other at risk populations who owing to their health vulnerabilities, lack of resources or social roles that make them dependent on others, experience stress in the face of climate change.
JCI Insight
September 2025
Division of Metabolism, Endocrinology & Diabetes, and.
Intracellular trafficking of secretory and membrane proteins from the endoplasmic reticulum (ER) to the cell surface, via the secretory pathway, is crucial to the differentiated function of epithelial tissues. In the thyroid gland, a prerequisite for such trafficking is proper protein folding in the ER, assisted by an array of ER molecular chaperones. One of the most abundant of these chaperones, Glucose-Regulated-Protein-170 (GRP170, encoded by Hyou1), is a noncanonical hsp70-like family member.
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