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http://dx.doi.org/10.1016/j.spinee.2019.05.004 | DOI Listing |
Front Surg
August 2025
Department of Orthopedics, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Background: Robot-assisted surgery has been increasingly applied in spinal surgery in recent years, but the differences in efficacy compared to conventional free-hand surgery remain unclear. This study aims to evaluate the impact of these two surgical approaches on spinal surgery patients by analyzing baseline characteristics, surgical data, short-term postoperative outcomes, and long-term functional recovery and pain relief.
Methods: This study first analyzed the differences in baseline characteristics and surgical data between the robot-assisted and conventional free-hand surgery groups, including age, gender, diabetes, hypertension, smoking, and alcohol consumption.
Cureus
August 2025
Department of Neurosurgery, Virginia Commonwealth University, Richmond, USA.
Background Anterior cervical discectomy and fusion (ACDF) is a common surgical procedure that patients undergo for cervical disc herniations and degenerative disc disease, aimed at relieving radicular symptoms and restoring cervical alignment. The impact of preoperative kyphotic cervical imbalance versus preoperative lordosis on postoperative radiographic outcomes in ACDF patients is unclear. The purpose of this study is to examine how preoperative cervical sagittal balance can influence quantified postoperative cervical sagittal balance.
View Article and Find Full Text PDFPaediatr Child Health
August 2025
Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Objectives: Cobb angle is a standard method for quantification of scoliosis in adolescent idiopathic scoliosis to guide treatment decisions. Precise and timely curve detection can ensure early referrals, amenable for bracing. Radiology reports serve as a guiding tool for family physicians to expedite specialist referrals.
View Article and Find Full Text PDFJ Pain Palliat Care Pharmacother
September 2025
Spine Unit, Orthopaedic Surgery and Traumatology Department, Catholic University and Polytechnic Hospital, Valencia, Spain.
Dexmedetomidine (DEX) has been proposed as an opioid-sparing adjunct after spinal fusion, but its efficacy across age groups is unclear. We conducted a systematic review and meta-analysis following PRISMA and registered in International Prospective Register of Systematic Reviews (PROSPERO) (CRD42024531252). Twelve studies (RCTs and cohorts; n=1,644) were included.
View Article and Find Full Text PDFRedox Biol
September 2025
Department of Spine Surgery, The Second Affiliated Hospital of Nantong University, Nantong First People's Hospital, Medical School of Nantong University, Nantong, Jiangsu, 226000, China; Research Institute for Spine and Spinal Cord Disease of Nantong University, Nantong, Jiangsu, 226000, China. Elec
Spinal cord injury (SCI) is a devastating condition characterized by the accumulation of myelin debris (MD), persistent neuroinflammation, and impaired neural regeneration. Although macrophages are pivotal for MD clearance, the impact of excessive MD phagocytosis on macrophage phenotype and function remains poorly understood. Building upon our prior evidence that exendin-4 (Ex-4), a glucagon-like peptide-1 receptor (GLP-1R) agonist, mitigates microglia-driven neuroinflammation post-SCI, this study elucidates the therapeutic efficacy and underlying mechanisms of Ex-4 in alleviating macrophage senescence, restoring efferocytotic capacity, and facilitating neural repair.
View Article and Find Full Text PDF