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Onchocerciasis is a neglected tropical disease with numerous symptoms and side effects, and when left untreated can lead to permanent blindness or skin disease. This database is an attempt to combine onchocerciasis prevalence data from peer-reviewed publications into a single open-source dataset. The process followed to extract and format the information has been detailed in this paper. A total of 14,043 unique location, diagnostic, age and sex-specific records from 1975-2017 have been collected, organized and marked for collapse where a single geo-position is shared between multiple records. The locations vary from single villages up to smaller administrative units and onchocerciasis control program-defined foci. This resulting database can be used to by the global health community to advance understanding of the distribution of onchocerciasis infection and disease.
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http://dx.doi.org/10.1038/s41597-019-0079-5 | DOI Listing |
PLoS Negl Trop Dis
September 2025
Institute of Immunology & Infection Research, University of Edinburgh, Ashworth Laboratories, Edinburgh, United Kingdom.
Background: Neglected tropical diseases (NTDs) are a group of 21 diseases affecting approximately 1.5 billion people globally. Significant progress has been made in their control: by March 2024, 50 countries had eliminated at least one NTD, with 13 of these countries eliminating at least two.
View Article and Find Full Text PDFInt J Infect Dis
August 2025
Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Objectives: The World Health Organization recommends monitoring infection and entomological indicators to evaluate onchocerciasis elimination. We reviewed trends in Guinea-Bissau since the onset of interventions to assess current progress toward elimination.
Methods: We collated programmatic, entomological, and epidemiological data from Guinea-Bissau, including Onchocerciasis Control Programme (OCP) records, impact data, and community-directed treatment with ivermectin (CDTi) data.
PLoS Negl Trop Dis
August 2025
Faculty of Medicine and Health Sciences, Global Health Institute, University of Antwerp, Belgium.
Background: Previous studies in the Bono Region (middle belt) of Ghana have reported persistent Onchocerca volvulus infection and associated morbidities after nearly three decades of ivermectin treatment. This study aimed to assess the usability, acceptability, and cost of the Ov16 SD BIOLINE rapid diagnostic test (Ov16 RDT) in onchocerciasis surveillance activities in the middle belt of Ghana.
Methodology: A cross-sectional study was conducted in 6 endemic communities in the Tain District and Wenchi Municipality.
Infect Dis Poverty
August 2025
TransVIHMIINSERM U1175French National Research Institute for Sustainable Development (IRD) U233, Montpellier University, 911 Avenue Agropolis, 34394, Montpellier, France.
Background: Loiasis affects millions in Central Africa and, though historically considered benign, emerging data suggest possible renal involvement. This study investigated the association between Loa microfilaremia and renal function.
Methods: We conducted a cross-sectional study in the Republic of Congo in May-June 2022.
Afr Health Sci
June 2025
Department of Medical Laboratory Science, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
Background: Onchocerciasis is a vector-borne disease caused by the tissue nematode Onchocerca volvulus. Despite its importance for targeted intervention, the national prevalence is not well addressed in Ethiopia.
Objective: This review aimed to determine the pooled prevalence of human onchocerciasis in Ethiopia.