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Objectives: The life expectancy and mortality rate always exhibit remarkable spatial variations. Their spatial distribution patterns and economic determinants in China were explored.
Methods: Four indexes including lifespan expectancy at birth (LEB), infant mortality rate (IMR), under-5 mortality rate (U5MR) and crude mortality rate (CMR) at county level in China were calculated. The spatial distribution patterns of these indexes were illustrated. Meanwhile, spatial regressive model was applied to explore the relations between major macroeconomic determinants and these indexes.
Results: Spatial dependence of these four indexes in China was identified, and the positive spatial autocorrelation indicated a clustering feature rather than stochastic distribution. Additionally, local Moran's I statistics revealed opposite local spatial clusters of LEB and IMR, U5MR in China, that LEB showed that high value clusters in the southwest and low value clusters in the eastern part and northern Xinjiang, and IMR/U5MR exhibited that low value clusters in the east and high value clusters in the west. The spatial regression revealed that income per capita influenced positively on LEB and CMR, and GDP per capita was associated positively with IMR and U5MR.
Conclusions: Geographical factors should be highly considered, and the L-L LEB or H-H IMR/U5MR clustered areas need to be integrated as a whole to formulate public health and economic development plans.
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http://dx.doi.org/10.1007/s00038-019-01251-y | DOI Listing |
Wounds
August 2025
Department of Nursing, Federal University of Ceará, Ceará, Brazil.
Background: Diabetic foot ulcers (DFUs) are a major clinical challenge, particularly among patients with refractory ulcers, that often lead to severe complications such as infection, amputation, and high mortality. Innovations supported by strong clinical evidence have the potential to improve healing outcomes, enhance quality of life, and reduce the economic burden on individuals and health care systems.
Objective: To describe the design of the concurrent optical and magnetic stimulation (COMS) therapy Investigational Device Exemption (IDE) study for refractory DFUs (MAVERICKS) trial.
Infect Dis Ther
September 2025
School of Biomedical Sciences, The Chinese University of Hong Kong (CUHK), Hong Kong SAR, China.
Introduction: The high mortality of Coronavirus Disease 2019 (COVID-19) highlights the need for safe and effective antiviral treatment. Small molecular antivirals (remdesivir, molnupiravir, nirmatrelvir/ritonavir) and immunomodulators (baricitinib, tocilizumab) have been developed or repurposed to suppress viral replication and ameliorate cytokine storms, respectively. Despite U.
View Article and Find Full Text PDFMikrochim Acta
September 2025
Pharmaceutical Analysis Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Salmonella Typhimurium (S. Typhimurium) is one of the most common food-borne diseases, highlighted as the top food-borne bacterial pathogen in the world with a low infectious dose (1 CFU) and high mortality rate. It is commonly associated with numerous foods such as dairy products, protein sources (multiple types of meat, poultry, and eggs), and bakery products.
View Article and Find Full Text PDFGeroscience
September 2025
Department of Emergency and Internal Medicine, Skåne University Hospital, Malmö, Sweden.
To evaluate a simplified version of the Clinical Frailty Scale (SCFS) among older adults presenting to the emergency department (ED) with acute dyspnea. In this retrospective single-center cohort study, we included patients from the Acute Dyspnea Study (ADYS) cohort. Severity of illness was assessed using the Medical Emergency Triage and Treatment System (METTS).
View Article and Find Full Text PDFGen Thorac Cardiovasc Surg
September 2025
Thoracic Surgery Department, Centre Hospitalier de la Cote Basque, 13, avenue de l'Interne Jacques Loeb, 64100, Bayonne, France.
Objective: Reduction of bleeding and prolonged air leak (>5 days) following major lung resection remains a challenge. Hemostasis and aerostasis devices can facilitate earlier pleural de-drainage and fast-track. Our objectives were to evaluate the efficacy of TenaTac (an elastic, adhering patch approved as a medical device) in reducing bleeding and prolonged air leak after major lung resection.
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