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We aimed to assess the functional performance and safety of a modified Woman's Condom (WC2) against the existing FC2 female condom. This randomized clinical trial enrolled 287 women in one South African site. The primary outcome of the study was the rate of female condom failure. Participants were asked to use five of each female condom type and to collect information on use in a condom log at home and were interviewed after use of each FC type. Noninferiority was demonstrated for the WC2 with respect to the reference condom FC2 for all condom functions. The WC2 was found to be superior to the FC2 reference condom for clinical failure ( = .000), total female condom failure ( = .001), misdirection ( = .000) and slippage ( = .004). The WC2 female condom performs as well as the FC2 female condom and offers good stability during use. Results from this study will inform further refinement of this female condom design, resulting in a new and potentially less expensive Woman's Condom.
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http://dx.doi.org/10.1080/13625187.2019.1610940 | DOI Listing |
Front Reprod Health
August 2025
Division of Epidemiology & Biostatistics, School of Public Health, University of Illinois Chicago, Chicago, IL, United States.
Introduction: Adolescent sexual and reproductive health in low- and middle-income countries is critical to address following the COVID-19 pandemic. Growing evidence of its' impact includes increased teenage pregnancies and higher rates of unsafe abortion. Our qualitative study sought to understand perspectives and behaviours around these escalations.
View Article and Find Full Text PDFFront Public Health
September 2025
School of Public Health, University of Rwanda, Kigali, Rwanda.
Background: Female sex workers (FSWs) in sub-Saharan Africa bear a disproportionate burden of HIV acquisition. While pre-exposure prophylaxis (PrEP) is increasingly accessible in the region, limited data exist on FSWs awareness of and willingness to use PrEP. This study aimed to assess PrEP awareness and willingness to use it, along with associated factors, among FSWs in Kigali, Rwanda.
View Article and Find Full Text PDFSex Transm Infect
September 2025
Division of Clinical Epidemiology, University Hospital Basel and University of Basel, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
Background: In 2018, Rwanda incorporated oral pre-exposure prophylaxis (PrEP) with tenofovir and emtricitabine (Truvada) into national HIV guidelines as part of a comprehensive HIV prevention programme for female sex workers (FSWs). This study assessed the impact of PrEP on HIV incidence among FSWs in urban Rwanda.
Methods: We conducted a retrospective cohort study among HIV-negative FSWs aged≥18 years at 20 health facilities in Kigali from January 2019 to October 2021.
Indian J Public Health
September 2025
Scientist G, Computing and Information Science Division, ICMR-National Institute of Epidemiology (ICMR-NIE), TNHB, Ayapakkam, Chennai, Tamil Nadu, India.
Background: Prisoners are considered a high-risk group for HIV, and global data suggest a higher HIV prevalence among prisoners. HIV Sentinel Surveillance (HSS) was initiated as a biennial activity among prisoners in India in 2019 to monitor HIV prevalence levels and trends in Indian prisons.
Objectives: The aim is to estimate the prevalence of HIV and syphilis and to assess the associated HIV risk behaviors among prisoners in South India.
Indian J Public Health
September 2025
Former Director, ICMR-National Institute for Research in Bacterial Infections (NIRBI), Kolkata, West Bengal, India.
Background: Female sex workers (FSWs) constitute a significant portion of high-risk groups (HRGs) in the districts of West Bengal, as indicated by HRG size mapping exercises.
Objectives: This study aimed to evaluate the knowledge of HIV/AIDS and condom usage practices among FSWs in clusters selected from districts in West Bengal for behavioural surveillance surveys (BSS)-lite.
Materials And Methods: BSS-lite was implemented in designated districts of West Bengal and interviews with 399 brothel and street-based FSWs from January to March 2020 were conducted utilizing computer-assisted personal interview or audio-computer assisted self-interview.