Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background And Aim: The risk and benefit of non-selective propranolol in patients with tense ascites are controversial. This study aimed to investigate the effect of propranolol as secondary prophylaxis on varix rebleeding and overall mortality in patients with tense ascites.
Methods: This study used a database of the Health Insurance Review and Assessment Service (HIRAS), which provides health insurance to 97.2% of the total population in Korea. A total of 80,071 patients first variceal bleeding as the first decompensated complication enrolled from 2007 to 2014.
Results: There were 2274 patients with large-volume ascites prescribed propranolol as secondary prophylaxis after first varix bleeding. The average prescription dose of propranolol as secondary prophylaxis was 74 mg/day in patients with large-volume ascites. The mean duration of rebleeding was 22.8 months. Result of analysis showed that low-dose propranolol (40-120 mg/day) compared to inadequate propranolol dose (<40 mg/day) as secondary prophylaxis decreased overall mortality and varix rebleeding in patients with tense ascites.
Conclusions: Low-dose propranolol (40-120 mg/day) as secondary prophylaxis for variceal re-bleeding decreased overall mortality and varix rebleeding recurrence in patients with tense ascites.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571569 | PMC |
| http://dx.doi.org/10.3390/jcm8050573 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparison of the effectiveness of first-line preventive treatment of migraine in primary care: study protocol for a pragmatic clinical trial (PREMI study).
Trials
August 2025
Fundació Institut Universitari per a La Recerca a L'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Gran Via de Les Corts Catalanes 587, Àtic, 08007, Barcelona, Spain.
Background: Migraine is a neurological disorder affecting approximately 12% of the population, more frequent in women, causing disability. Preventive treatment is recommended to prevent chronification and analgesics' abuse and to improve quality of life, but not all candidates receive it. Common preventive drugs include amitriptyline, flunarizine, propranolol, and topiramate.
View Article and Find Full Text PDF[Arthrofibrosis after total knee arthroplasty-Diagnosis and management].
Orthopadie (Heidelb)
August 2025
UniversitätsCentrum für Orthopädie, Unfall- & Plastische Chirurgie, Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden, Anstalt des öffentlichen Rechts des Freistaates Sachsen, Fetscherstraße 74, 01307, Dresden, Deutschland.
Arthrofibrosis is a common complication following total knee arthroplasty (approximately 5%), characterized by painful limitation of range of motion and increased soft tissue fibrosis. Women are affected more frequently than men. A distinction is made between primary (early postoperative, global) and secondary forms (mechanical/infectious causes).
View Article and Find Full Text PDFJanus Electrocatalytic Membrane Enables Tunable Redox via Sequential Tactics toward Ultrafast Water Decontamination.
Environ Sci Technol
August 2025
State Key Laboratory of Regional Environment and Sustainability, School of Environment, Tsinghua University, Beijing 100084, China.
Emerging contaminants (ECs) in water are a prominent environmental concern worldwide. Despite advanced oxidation or reduction being appealing transformation approaches, existing technologies face challenges in adaptability to the removal of both electron-rich ECs and ECs with electron-withdrawing moieties. Here, a Janus electrocatalytic membrane was fabricated to induce hydroxyl radicals (OH) and atomic hydrogen (H*) simultaneously and tune redox processes via sequential tactics to achieve adaptable and ultrafast removal of diverse ECs.
View Article and Find Full Text PDFLong term (TEN YEARS) follow-up in a trembling patient with parkinsonian signs without dopaminergic denervation.
Clin Park Relat Disord
July 2025
IRCCS Neuromed, Pozzilli, IS, Italy.
Some patients presenting with Parkinson's disease (PD)-like features do not exhibit dopaminergic denervation, complicating clinical categorization. This case report describes a patient with a long-standing upper limb action tremor accompanied by parkinsonian signs, but without evidence of dopaminergic denervation, followed over an extended period of ten years. The case highlights the diagnostic challenges and underscores the importance of longitudinal observation in such atypical presentations.
View Article and Find Full Text PDFThe relaxant effect of the extract of petal on Wistar rats airway smooth muscle and its possible mechanisms.
Avicenna J Phytomed
January 2025
Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Objective: Obstructive pulmonary diseases are characterized by airflow limitation secondary to airway wall thickening, airway narrowing and increased mucus secretion. Saffron ( L.) has shown different effects including anti-inflammatory, antioxidant, and immunomodulatory properties and promising effects for treating multiple disorders.
View Article and Find Full Text PDF