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Importance: Handgrip dynamometry is probably the most commonly used method to characterize overall human muscle strength.
Objective: To compare and summarize grip strength measurements obtained from two population-based studies.
Design: Secondary data analysis.
Setting And Participants: Data from (1) the 2011-2014 National Health and Nutrition Examination Survey (NHANES) with 13,918 participants and (2) the 2011 normative phase of the National Institutes of Health (NIH) Toolbox project with 3,594 participants.
Outcomes And Measures: The NHANES values used were the mean and best of three trials; the NIH Toolbox value used was the one maximum trial after a practice trial.
Results: General linear model analysis revealed that values obtained from the NIH Toolbox differed from NHANES best values but not from NHANES mean values. The analysis also indicated, regardless of the values used, that grip strength differed significantly between dominant and nondominant sides, males and females, and age groups. We provide updated reference values for handgrip strength.
Conclusions And Relevance: On the basis of these analyses, we summarize grip strength measures obtained from the NHANES and NIH Toolbox for side, gender, and age group strata. Reference values are essential to assist in the interpretation of testing results and clinical decision making.
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http://dx.doi.org/10.5014/ajot.2019.029538 | DOI Listing |
Neuroimage Clin
September 2025
Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Objectives: To examine associations between low cognitive-performance and regional-and network-level brain changes at ages 9-10 in very-preterm, moderately-preterm, and full-term children, and explore whether these alterations predict ASD/ADHD symptoms at age 12.
Methods: This longitudinal population-based study included 9-10-year-old U.S.
Sleep Adv
August 2025
Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT, United States.
Study Objectives: Research linking children's sleep to cognitive outcomes is inconsistent and has largely focused on one aspect of sleep, such as duration, rather than measuring multiple dimensions of sleep health. We hypothesized that children's sleep health would be positively associated with inhibitory control and cognitive functioning.
Method: We cross-sectionally assessed 1595 participants (ages 7-11) from the Environmental influences on Child Health Outcomes cohort using the NIH Toolbox Cognition Battery, Environmental influences on Child Health Outcomes Sleep Health of Children and Adolescents questionnaire, and Patient Reported Outcome Measurement Information System Sleep Disturbance/Sleep-related Impairment instruments.
Mult Scler Relat Disord
August 2025
Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA.
Background: Cognitive impairment is common in multiple sclerosis (MS) and affects daily functioning. Compensatory cognitive strategies can help mitigate these challenges, but their naturalistic use and predictors remain unclear. This study aimed to examine the frequency and types of strategies used and to determine whether demographics, objective cognitive function, or perceived cognitive function are independently associated with the use of compensatory strategies.
View Article and Find Full Text PDFJ Psychopathol Clin Sci
September 2025
Department of Psychology, University of Illinois Chicago.
Mood disorders (MDs) such as major depressive disorder and bipolar disorder are associated with significant functional impairments, particularly in cognition, which can adversely affect daily functioning and social interactions. This study aims to predict cognitive functioning prospectively in individuals with MDs using passive data from smartphone typing dynamics. Over a period of approximately 28 days, participants ( = 127) utilized the BiAffect keyboard, which captured typing metadata such as keystroke timestamps and accelerometer data during typing sessions, while also undergoing in-lab neuropsychological assessments twice (at least 14 days apart).
View Article and Find Full Text PDFJ Cell Sci
September 2025
Department of Biology, Duke University, Box 90338, Durham, NC 27708, USA.
Basement membranes (BMs) underlie or surround most tissues. They are formed of secreted proteins that associate with cell surfaces and are the most ancient animal extracellular matrix. Laminin and collagen IV are core components that polymerize into self-associating networks, providing BMs with an organizing scaffold and tensile strength.
View Article and Find Full Text PDF