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Objective: Right-sided heart failure develops in lung transplantation candidates on prolonged peripheral extracorporeal membrane oxygenation support and is a major determinant of mortality. The use of central venoarterial extracorporeal membrane oxygenation for bridging of right-sided heart failure to lung transplantation was evaluated.
Design: Retrospective case series and literature review.
Setting: A single tertiary care university hospital.
Participants: The study comprised lung transplantation candidates on extracorporeal membrane oxygenation bridging who developed right-sided heart failure.
Interventions: Central venoarterial extracorporeal membrane oxygenation.
Measurements And Main Results: Of 6 patients who underwent the study protocol, 3 were bridged successfully to lung transplantation and 1 was bridged to recovery.
Conclusions: The study demonstrates that central extracorporeal membrane oxygenation may be a feasible option for bridging of right-sided heart failure to lung transplantation.
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http://dx.doi.org/10.1053/j.jvca.2019.01.059 | DOI Listing |
Introduction: Advances in neonatology, neonatal surgery, and extracorporeal membrane oxygenation (ECMO) have improved the prognosis of congenital diaphragmatic hernia (CDH). However, CDH survivors are at considerable risk of long-term neurological morbidity. Magnetic resonance imaging (MRI) abnormalities are reported in up to 84% of CDH-survivors but have only been rarely compared with neurodevelopmental outcomes.
View Article and Find Full Text PDFHum Genet
September 2025
Prenatal Diagnostic Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, 510620, Guangdong, China.
This study aims to assess the genetic burden of fetal congenital diaphragmatic hernia (CDH) and identify prenatal, perinatal, and postnatal predictors to improve early diagnosis, monitoring, and intervention. This study included 130 CDH fetuses who underwent invasive prenatal diagnosis, with fetal prognosis evaluated using imaging parameters such as observed-to-expected lung-to-head ratio (o/e LHR), observed-to-expected total lung volume (o/e TLV), and percent predicted lung volume (PPLV). Clinical outcomes included neonatal outcomes, extracorporeal membrane oxygenation (ECMO) requirement, and post-neonatal prognosis.
View Article and Find Full Text PDFPerfusion
September 2025
Department of Adult Critical Care, Guy's and St Thomas' NHS Foundation Trust, London, UK.
IntroductionWe report the successful use of erector spinae (ESP) plane block in the management of a patient with severe respiratory failure secondary to chest trauma requiring invasive ventilation and Veno-venous extracorporeal membrane oxygenation (V-V ECMO).Case reportA 64-year-old man with flail chest and severe respiratory failure required V-V ECMO. An ESP plane block on day 3 enabled extubation, mobilisation, and secretion clearance, leading to ECMO weaning after six days and discharge 18 days post-injury.
View Article and Find Full Text PDFJACC Case Rep
September 2025
Division of Pediatric Cardiology, Department of Pediatrics, Congenital Heart Center, University of Florida, Gainesville, Florida, USA.
Left atrial (LA) decompression is often performed in patients on venoarterial extracorporeal membrane oxygenation to help offload the left ventricle. Atrial septal stents may be used to ensure the adequacy of LA decompression; however, if there is cardiopulmonary recovery and extracorporeal membrane oxygenation support is no longer needed, the stents require removal. We describe 3 pediatric patients who required venoarterial extracorporeal membrane oxygenation support and atrial septal stent placement who underwent successful transcatheter removal of the stents after cardiac recovery.
View Article and Find Full Text PDFZ Geburtshilfe Neonatol
September 2025
Department of Critical Care Medicine, Weifang People's Hospital, Weifang, China.
Amniotic fluid embolism (AFE) is a critical obstetric complication characterized by the entry of amniotic fluid and its components into maternal circulation during parturition, leading to acute cardiopulmonary failure, disseminated intravascular coagulation (DIC), and anaphylactic shock. Affected patients typically exhibit abrupt onset, rapid progression, and exceedingly high mortality. Early recognition and prompt intervention are pivotal in AFE management.
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