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A workshop was held in Wageningen, The Netherlands, in September 2017 to collate data and literature on three aquatic ecosystem types (agricultural drainage ditches, urban floodplains, and urban estuaries), and develop a general framework for the assessment of multiple stressors on the structure and functioning of these systems. An assessment framework considering multiple stressors is crucial for our understanding of ecosystem responses within a multiply stressed environment, and to inform appropriate environmental management strategies. The framework consists of two components: (i) problem identification and (ii) impact assessment. Both assessments together proceed through the following steps: 1) ecosystem selection; 2) identification of stressors and quantification of their intensity; 3) identification of receptors or sensitive groups for each stressor; 4) identification of stressor-response relationships and their potential interactions; 5) construction of an ecological model that includes relevant functional groups and endpoints; 6) prediction of impacts of multiple stressors, 7) confirmation of these predictions with experimental and monitoring data, and 8) potential adjustment of the ecological model. Steps 7 and 8 allow the assessment to be adaptive and can be repeated until a satisfactory match between model predictions and experimental and monitoring data has been obtained. This paper is the preface of the MAEGA (Making Aquatic Ecosystems Great Again) special section that includes three associated papers which are also published in this volume, which present applications of the framework for each of the three aquatic systems.
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http://dx.doi.org/10.1016/j.scitotenv.2019.02.455 | DOI Listing |
Drug Alcohol Depend
August 2025
Division of General Pediatrics and Adolescent Health, Department of Pediatrics, University of Minnesota, 717 Delaware St. SE, Minneapolis, MN 55414, United States. Electronic address:
Purpose: Cannabis use is common in adolescence and has been associated with negative health effects, and higher prevalence has been seen among marginalized youth. Research has not examined regular use or attitudes promoting use, particularly taking an approach grounded in intersectionality and minority stressors. The present study examines how regular cannabis use, perceptions of risk, approval from parents and friends, and peer norms of use differ across multiple social positions.
View Article and Find Full Text PDFGeriatr Gerontol Int
September 2025
Department of Internal Medicine, Chung-Ang University Hospital, Seoul, South Korea.
Aim: Patients undergoing maintenance hemodialysis (MHD) often have multiple comorbidities and are vulnerable to minor stressors that frequently result in hospitalization. Recent advances have enabled the easy estimation of body composition in clinical settings. This study retrospectively investigated changes in body composition associated with hospitalization in patients receiving MHD.
View Article and Find Full Text PDFProteomics
September 2025
Department of Biochemistry and Molecular Biology, Michael Smith Laboratories, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada.
Honey bees (Apis mellifera) are vital pollinators in fruit-producing agroecosystems like highbush blueberry (HBB) and cranberry (CRA). However, their health is threatened by multiple interacting stressors, including pesticides, pathogens, and nutritional changes. We tested the hypothesis that distinct agricultural ecosystems-with different combinations of agrochemical exposure, pathogen loads, and floral resources-elicit ecosystem-specific, tissue-level molecular responses in honey bees.
View Article and Find Full Text PDFInt Immunopharmacol
September 2025
Amity Institute of Pharmacy, Amity University Kolkata, Major Arterial Road, Action Area II, Newtown, Kolkata 700135, West Bengal, India. Electronic address:
Diabetes mellitus (DM) and multiple sclerosis (MS), while affecting metabolic and neurological systems respectively, share convergent immunometabolic pathways. This review synthesizes recent evidence elucidating overlapping mechanisms linking DM and MS, emphasizing metabolic dysfunction and systemic inflammation, with therapeutic potential of lifestyle interventions alongside pharmacotherapy. A comprehensive literature analysis examined shared pathogenesis through recent studies.
View Article and Find Full Text PDFUnlabelled: Repeated exposure to stress disrupts cognitive processes, including attention and working memory. A key mechanism supporting these functions is the ability of neurons to sustain action potential firing, even after a stimulus is no longer present. How stress impacts this persistent neuronal activity is currently unknown.
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