The Relationship between Liver Injury and Serum Levels of C-Reactive Protein and Procalcitonin in Patients with Acute Pancreatitis.

Acute pancreatitis (AP) can cause damage to multiple organs in the whole body, and the liver is one of the most frequently affected by AP. Ninety-six AP patients, consisting 67 patients with liver injury, were enrolled. They were classified as mild AP (MAP) and severe AP (SAP), according to the Atlanta Revised Classification, with 50 healthy subjects serving as the controls. The serum levels of C-reactive protein (CRP) and procalcitonin (PCT) were measured by ELISA. Serum levels of alanine aminotransferase (ALT), alkaline phosphatase (AKP) and aspartate aminotransferase (AST) were also analysed. AP patients had high incidence of liver injury which was greater in SAP than in MAP patients, the levels of serum CRP and serum PCT were positively correlated to ALT, AKP and AST levels in AP patients with liver injury. Serum levels of CRP and PCT may be used as indicators of liver injury in the AP patients.