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This paper describes and analyzes the psychiatric reform process in three Latin American countries (Brazil, Chile and Colombia) based on the Caracas Declaration of 1990. It compares the psychiatric reform processes in these three countries and highlights the role of national mental health laws in these processes. Our goal when investigating the experiences in other countries of Latin America is to draw conclusions for the Argentine psychiatric reform and for the future of such reforms in the region.
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Int J Law Psychiatry
September 2025
Health New Zealand, Otago University, New Zealand.
New Zealand, as well as other jurisdictions, are revisiting their decision-making capacity law regimes. Currently several strands of New Zealand capacity law are under review. Reforms could impact many people across many domains of decision-making.
View Article and Find Full Text PDFCien Saude Colet
August 2025
Instituto de Medicina Social, Universidade do Estado do Rio de Janeiro. Rio de Janeiro RJ Brasil.
Deinstitutionalization enables the removal of users from asylums with the support of the Psychosocial Care Network (PCN), which is based on the Psychosocial Care Centers (PCCs). One of the current impasses is the emergence of private/religious institutions that are updating the asylum model. In order to analyze what leads to neo-institutionalization in these locations, an ethnographical study was carried out on nine cases in four PCCs of the three PCNs in the city of Rio de Janeiro, through scrutiny of medical records, interviews with the patient, family members, PCC technicians and managers of the asylums per se.
View Article and Find Full Text PDFPhytother Res
September 2025
Department of Pharmacy, Shanghai General Hospital Jiuquan Hospital (The People's Hospital of Jiuquan), Jiuquan, China.
To evaluate the efficacy and explore the potential mechanism of curcumin for the treatment and prevention of NSCLC. We searched six databases thoroughly for articles published before December 2024. Stata 15.
View Article and Find Full Text PDFInt Rev Psychiatry
September 2025
Neuropsychiatry Department, Okasha Institute of Psychiatry, Ain Shams University, Cairo, Egypt.
This review traces the evolution of psychiatry in Egypt and the broader Arab region from 1994 to 2024, offering a comprehensive analysis of reforms in mental health policy, clinical infrastructure, education, legislation and workforce development. This paper examines key challenges, including service fragmentation, sociocultural stigma, refugee mental health and underinvestment. It highlights current contradictions in the field, such as increased demand, limited access and the dominance of imported psychiatric models with insufficient cultural adaptation.
View Article and Find Full Text PDFNeurochem Res
September 2025
Department of Psychiatry, Shenzhen University General Hospital, Shenzhen University, Shenzhen, 518055, Guangdong, China.
Depression is a significant global health concern that extends beyond mere neurotransmitter imbalances, as the significance of autophagy in cellular recycling is increasingly recognized as pivotal in its pathogenesis and therapeutic intervention. This review thoroughly integrates the insights on how various antidepressants, such as SSRIs, SNRIs, and TCAs, confer therapeutic efficacy through modulation of autophagy pathways. We present evidence indicating that these pharmacological agents can augment autophagic flux, facilitate the clearance of neurotoxic protein aggregates, mitigate neuroinflammation, and enhance mitochondrial functionality, all of which represent critical elements of depressive pathology.
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