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Background: Human intestinal spirochetosis is a condition defined by the presence of spirochetes attached to the colonic epithelium. and may cause the disease in humans.
Case Report: We describe the case of a 58-year-old patient who presented with epigastric abdominal pain and diarrhoea. He was thought to be having a myocardial infarction and underwent an angiogram with subsequent stenting of the circumflex coronary artery. However, the pain and diarrhoea were still present after the procedure and the patient now had sepsis. An exploratory laparotomy was inconclusive. The patient improved on intravenous antibiotics and was discharged, but returned to the emergency department 2 days later with the same complaints. He was then admitted to an internal medicine ward where the diagnosis of intestinal spirochetosis was made. The patient was started on metronidazol and completed a 10-day antibiotic course with full recovery of his symptoms.
Conclusion: This case highlights the importance of an internist-based approach that could have prevented two invasive procedures and the accompanying risks.
Learning Points: Uncommon causes of diarrhoea are a diagnostic challenge.Errors of clinical judgement can lead to invasive and potentially harmful procedures.An internist-based approach can prevent diagnostic mistakes and be in the patient's best interests.
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http://dx.doi.org/10.12890/2016_000501 | DOI Listing |
Clin Transl Gastroenterol
September 2025
Lynda K and David M Underwood Center for Digestive Health, Houston Methodist, Houston, TX, USA.
Introduction: Pharmacological therapies for chronic idiopathic constipation (CIC) are useful, but many patients report dissatisfaction from a lack of efficacy and occurrence of adverse events. The vibrating capsule (VC) is an FDA approved non-pharmacologic, treatment for CIC. However, its long-term usefulness in a community setting is unknown.
View Article and Find Full Text PDFClin Toxicol (Phila)
September 2025
Rocky Mountain Poison and Drug Safety, Denver Health and Hospital Authority, Denver, CO, USA.
Introduction: The clinical presentations associated with spp. (true morel) and spp. (false morel) mushroom ingestions are incompletely characterized.
View Article and Find Full Text PDFBMC Infect Dis
September 2025
Infectious Diseases Research Center (IDRC), Arak University of Medical Sciences, Arak, Iran.
Background: Giardiasis is recognized as the most prevalent enteric protozoal infection worldwide. Although gastrointestinal symptoms are the most common manifestations of giardiasis, several studies have reported cases of urticaria associated with this infection. Urticaria is a common mast cell-dependent disorder characterized by wheals, angioedema, or both.
View Article and Find Full Text PDFJ Pediatr Gastroenterol Nutr
September 2025
Division of Gastroenterology, Hepatology, and Nutrition; Children's Mercy Kansas City, Kansas City, Missouri, USA.
Objective: Irritable bowel syndrome (IBS) is divided into subcategories recognizing differences in stool frequency and form. The third IBS symptom, a change in pain with stools may also introduce heterogeneity and has not been well described in youth with IBS. The current study was undertaken to assess changes in pain with stooling and the presence of nocturnal stools.
View Article and Find Full Text PDFViruses
July 2025
Faculty of Medicine, The Hashemite University, Zarqa 13133, Jordan.
Background: Cytomegalovirus (CMV) colitis is commonly seen in patients who are immunodeficient or have inflammatory bowel disease. Among the gastrointestinal sites affected by CMV, the colon is the most frequently affected, though rectal involvement is relatively rare. Reactivated CMV proctitis primarily occurs in elderly patients with comorbidities and is quite uncommon in immunocompetent individuals.
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