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http://dx.doi.org/10.1080/13696998.2019.1576181 | DOI Listing |
Eur J Clin Pharmacol
September 2025
Hospital Management Research Center, Health Management Research Institute, Iran University of Medical Sciences, Tehran, Iran.
Introduction: Metastatic breast cancer (mBC) is a major global health challenge. Antibody-drug conjugates (ADCs), including trastuzumab emtansine (T-DM1), trastuzumab deruxtecan (T-DXd), and sacituzumab govitecan (SG), offer clinical benefits but are associated with high costs, making cost-effectiveness assessments essential for policy decisions.
Methods: This systematic review analyzed economic evaluations comparing T-DM1, T-DXd, and SG with conventional treatments in breast cancer.
AJNR Am J Neuroradiol
September 2025
From the Department of Diagnostic Radiology (E.W., A.D., C.J.M., M.C., M.K.G.) and Department of Pathology (L.Y.B.), MD Anderson Cancer Center, Houston, TX, USA; Department of Radiology and Biomedical Imaging (L.T., J.M.J), Yale University, New Haven, CT, USA.
Background And Purpose: Brain imaging with MRI or CT is standard in screening for intracranial disease among ambulatory cancer patients. Although MRI offers greater sensitivity, CT is frequently employed due to its accessibility, affordability, and faster acquisition time. However, the necessity of routinely performing a non-contrast CT with the contrast-enhanced study is unknown.
View Article and Find Full Text PDFJCO Glob Oncol
May 2025
Department of Obstetrics and Gynaecology, Stanford University School of Medicine, Stanford, CA.
Purpose: Expanding high-risk human papillomavirus (HPV) vaccine coverage in resource-constrained settings is critical to bridging the cervical cancer gap and achieving the global action plan for elimination. Mobile health (mHealth) technology via short message services (SMS) has the potential to improve HPV vaccination uptake. The mHealth-HPVac study evaluated the effectiveness of mHealth interventions in increasing HPV vaccine uptake among mothers of unvaccinated girls aged 9-14 years in Lagos, Nigeria.
View Article and Find Full Text PDFJ Med Screen
September 2025
The Cancer Registry of Norway, Department of Screening programs, Norwegian Institute of Public Health, Oslo, Norway.
ObjectiveTo study the implications of implementing artificial intelligence (AI) as a decision support tool in the Norwegian breast cancer screening program concerning cost-effectiveness and time savings for radiologists.MethodsIn a decision tree model using recent data from AI vendors and the Cancer Registry of Norway, and assuming equal effectiveness of radiologists plus AI compared to standard practice, we simulated costs, effects and radiologist person-years over the next 20 years under different scenarios: 1) Assuming a €1 additional running cost of AI instead of the €3 assumed in the base case, 2) varying the AI-score thresholds for single vs. double readings, 3) varying the consensus and recall rates, and 4) reductions in the interval cancer rate compared to standard practice.
View Article and Find Full Text PDFIEEE Trans Neural Syst Rehabil Eng
September 2025
Obstructive sleep apnea (OSA), one of the most common sleep disorders globally, is closely linked to brain function. Resting-state electroencephalography (EEG), due to its convenience, cost-effectiveness, and high temporal resolution, serves as a valuable tool for exploring the human brain function. This study utilized a large cohort with 968 participants who joined in 15-minute daytime resting-state EEG acquisition and overnight polysomnography (PSG) monitoring.
View Article and Find Full Text PDF